Effect of Resistance Training Variable Manipulation in Postmenopausal Breast Cancer Survivors.
NCT ID: NCT03644329
Last Updated: 2018-08-23
Study Results
Results pending
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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Recruitment Status
UNKNOWN
Clinical Phase
NA
Total Enrollment
80 participants
Study Classification
INTERVENTIONAL
Study Start Date
2018-05-13
Study Completion Date
2019-12-20
Brief Summary
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This study intends to evaluate the impact of resistance training variable manipulation (intensity and volume) on body composition, fatigability and functional capacity in postmenopausal breast cancer survivors.
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Detailed Description
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The treatment for breast cancer (chemotherapy, radiotherapy and hormone therapy) provokes collateral effects,such as muscle mass and strength losses, increase of fat mass, fatigue and disability and reduced quality of life in postmenopausal breast cancer survivors. The resistance training is assumed as a non-pharmacologic interventions in postmenopausal breast cancer survivors. However, it is unclear whether the manipulation of training variables (intensity and volume) maximize the effects of resistance training on body composition, fatigability and functional capacity in postmenopausal breast cancer survivors.
Conditions
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Breast Cancer Survivors
Postmenopause
Study Design
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Allocation Method
RANDOMIZED
Intervention Model
PARALLEL
Primary Study Purpose
SUPPORTIVE_CARE
Blinding Strategy
NONE
Study Groups
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Control group, CT
In the CT, the postmenopausal breast cancer survivers does not perform exercise.
Group Type
OTHER
Control group
Intervention Type
OTHER
The volunteers will not performed the interventions.
Lower-load resistance training (LL)
In the LL, the postmenopausal breast cancer survivers will be submitted to 12 weeks of resistance training with low loads ( i.e. three sets with 30% of one-repetition maximum).
Group Type
EXPERIMENTAL
Lower-load resistance training (LL)
Intervention Type
OTHER
The volunteers will be perform the resistance training, three times a week for 12 weeks on non-consecutive days, three sets with 30% of 1RM and repetition until or close to failure in each set and 1.5-min of rest between sets and exercises.
Higher-load resistance training (HL)
In the HL, the postmenopausal breast cancer survivers will be submitted to 12 weeks of resistance training with high loads (i.e. three sets with 80% of one maximum repetition).
Group Type
EXPERIMENTAL
Higher-load resistance training (HL)
Intervention Type
OTHER
The volunteers will be perform the resistance training, three times a week for 12 weeks on non-consecutive days, three sets with 80% of 1RM and repetition until or close to failure in each set and 1.5-min of rest between sets and exercises.
Higher-volume resistance training (HV)
In the HV, the postmenopause breast cancer survivers will be submitted to 12 weeks of resistance training with high volume ( i.e. six sets with 80% one maximum repetition).
Group Type
EXPERIMENTAL
Higher-volume resistance training (HV)
Intervention Type
OTHER
The volunteers will be perform the resistance training, three times a week for 12 weeks on non-consecutive days, six sets with 80% of 1RM and repetition until or close to failure in each set and 1.5-min of rest between sets and exercises.
Interventions
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Control group
The volunteers will not performed the interventions.
Intervention Type
OTHER
Lower-load resistance training (LL)
The volunteers will be perform the resistance training, three times a week for 12 weeks on non-consecutive days, three sets with 30% of 1RM and repetition until or close to failure in each set and 1.5-min of rest between sets and exercises.
Intervention Type
OTHER
Higher-load resistance training (HL)
The volunteers will be perform the resistance training, three times a week for 12 weeks on non-consecutive days, three sets with 80% of 1RM and repetition until or close to failure in each set and 1.5-min of rest between sets and exercises.
Intervention Type
OTHER
Higher-volume resistance training (HV)
The volunteers will be perform the resistance training, three times a week for 12 weeks on non-consecutive days, six sets with 80% of 1RM and repetition until or close to failure in each set and 1.5-min of rest between sets and exercises.
Intervention Type
OTHER
Eligibility Criteria
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Inclusion Criteria
* Postmenopausal breast cancer survivors;
* No supervised or unsupervised exercise at least for six months prior to the study.
* No supervised or unsupervised exercise at least for six months prior to the study.
Exclusion Criteria
* Alcoholics;
* No controlled blood pressure and glucose;
* Presence of myopathies, arthropathies, and neuropathies;
* Presence of muscle, thromboembolic and gastrointestinal disorders, infection diseases.
* No controlled blood pressure and glucose;
* Presence of myopathies, arthropathies, and neuropathies;
* Presence of muscle, thromboembolic and gastrointestinal disorders, infection diseases.
Minimum Eligible Age
50 Years
Eligible Sex
FEMALE
Accepts Healthy Volunteers
No
Sponsors
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Universidade Federal do Triangulo Mineiro
OTHER
Sponsor Role
lead
Responsible Party
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Fábio Lera Orsatti
Principal Investigator
Responsibility Role
PRINCIPAL_INVESTIGATOR
Principal Investigators
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Fábio L Orsatti, PhD
Role: PRINCIPAL_INVESTIGATOR
Federal University of Triângulo Mineiro
Locations
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Post-degree program in physical education
Uberaba, MG - Minas Gerais, Brazil
Site Status
RECRUITING
Countries
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Brazil
Central Contacts
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Facility Contacts
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Other Identifiers
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CAAE: 82691818.0.0000.5154
Identifier Type: -
Identifier Source: org_study_id
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RECRUITING
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