Additive Effect of Intravenous Acetaminophen on Postoperative Pain Control
NCT ID: NCT03644147
Last Updated: 2021-01-08
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
84 participants
INTERVENTIONAL
2018-08-27
2021-01-07
Brief Summary
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Participants undergoing laparoscopic hysterectomy will be randomly assigned to treatment group or control group. After end of surgery, acetaminophen or normal saline (placebo) will be administered intravenously depending on the group assigned.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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Treatment
Patients in this group will receive 1 gram of acetaminophen intravenously after the end of surgery.
Acetaminophen
Acetaminophen will be intravenously administrated to treatment group after the end of surgery.
Control
Patients in this group will receive 100 ml of normal saline intravenously after the end of surgery.
No interventions assigned to this group
Interventions
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Acetaminophen
Acetaminophen will be intravenously administrated to treatment group after the end of surgery.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Chronic kidney disease (GFR \< 30 ml/min/1.73m2)
* History of drug allergy
* Chronic pain lasting more than 3 months
* Conversion to laparotomy
* Complex surgery (co-operation with colon surgeon or urologist)
* Limitation in expressing pain
19 Years
80 Years
FEMALE
No
Sponsors
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Seoul National University Hospital
OTHER
Responsible Party
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Jin-Tae Kim
Professor
Principal Investigators
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Jin-Tae Kim, Pf.
Role: PRINCIPAL_INVESTIGATOR
Seoul National University Hospital
Locations
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Seoul National University Hospital
Seoul, , South Korea
Countries
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References
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Nam S, Yoo S, Park SK, Kim JT. Additive effect of a single intravenous dose of acetaminophen administered at the end of laparoscopic hysterectomy on postoperative pain control with nefopam and fentanyl-based patient-controlled analgesia: a double-blind, randomized controlled trial. BMC Anesthesiol. 2025 Feb 20;25(1):88. doi: 10.1186/s12871-025-02971-w.
Other Identifiers
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H-1807-151-961
Identifier Type: -
Identifier Source: org_study_id
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