A Comparison of Custom-manufactured vs. Off-the-rack (OTR) Compression Hosiery for Initial Management of Venous Disease

NCT ID: NCT03630185

Last Updated: 2020-02-17

Study Results

Results available

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Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

8 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-04-25

Study Completion Date

2018-11-30

Brief Summary

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The purpose of this research study is to assess the efficacy of custom-manufactured compression hosiery (also known as compression stockings) compared to similar off-the-rack (OTR) compression stockings.

Detailed Description

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Conditions

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Venous Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Custom-manufactured compression hosiery (Isobar)

The custom-fitted garment is manufactured specifically for each patient based on measurements taken with a 3-dimensional volumetric laser scan of the extremity, and can be sized individually to each limb.

Group Type EXPERIMENTAL

Custom-manufactured compression hosiery (Isobar)

Intervention Type DEVICE

The custom-fitted garment is manufactured specifically for each patient based on measurements taken with a 3-dimensional volumetric laser scan of the extremity, and can be sized individually to each limb.

Off-the-rack stockings (Sigvaris)

Currently available off-the-rack compression hosiery are manufactured in eight fixed sizes (S-XLFC) that cannot be varied in size over their length to accommodate unusual anatomic patterns (eg., small ankle with large calf or vice versa) and may not achieve a comfortable fit that meets the compression goal over a uniform distribution of the limb.

Group Type ACTIVE_COMPARATOR

Off-the-rack stockings (Sigvaris)

Intervention Type DEVICE

Currently available off-the-rack compression hosiery are manufactured in eight fixed sizes (S-XLFC) that cannot be varied in size over their length to accommodate unusual anatomic patterns (eg., small ankle with large calf or vice versa) and may not achieve a comfortable fit that meets the compression goal over a uniform distribution of the limb.

Interventions

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Custom-manufactured compression hosiery (Isobar)

The custom-fitted garment is manufactured specifically for each patient based on measurements taken with a 3-dimensional volumetric laser scan of the extremity, and can be sized individually to each limb.

Intervention Type DEVICE

Off-the-rack stockings (Sigvaris)

Currently available off-the-rack compression hosiery are manufactured in eight fixed sizes (S-XLFC) that cannot be varied in size over their length to accommodate unusual anatomic patterns (eg., small ankle with large calf or vice versa) and may not achieve a comfortable fit that meets the compression goal over a uniform distribution of the limb.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Ability to comprehend and sign an informed consent and complete study questionnaires
* Patient is participating in usual work and home activities with no changes anticipated for the duration of the study
* The use of compression stocking is prescribed in accordance with the usual practice and management of venous disorders
* The patient will confirm they are willing to pay for the compression stockings.

Exclusion Criteria

* The patient has a known allergy to any component of the stocking (latex, etc)
* The patient has non-venous source of pain in either leg that could, in the opinion of the investigator, confound the results of the study i.e.Neuropathy, Arterial insufficiency, Diabetes
* The patient is confined to bed
* The patient has uncontrolled Congestive Heart Failure
* The patient has acute dermatitis
* The patient has weeping dermatosis
* Patients with venous ulcers will be excluded.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The University of Texas Health Science Center, Houston

OTHER

Sponsor Role lead

Responsible Party

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Stuart A Harlin

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Stuart A Harlin, MD

Role: PRINCIPAL_INVESTIGATOR

The University of Texas Health Science Center, Houston

Locations

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The University of Texas Health Science Center at Houston

Houston, Texas, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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HSC-MS-17-0015

Identifier Type: -

Identifier Source: org_study_id

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