Plasma and Intrapulmonary Concentrations Study of WCK 5222

NCT ID: NCT03630094

Last Updated: 2018-08-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

36 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-03-31

Study Completion Date

2017-07-30

Brief Summary

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This is a Phase 1, multiple dose, open-label pharmacokinetic study in healthy adult male and female subjects.

Detailed Description

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Conditions

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PHA1A

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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FEP-ZID via intravenous

total of 7 doses of FEP-ZID via intravenous infusion over 60 min at q8hr dosing regimen

Group Type EXPERIMENTAL

FEP-ZID

Intervention Type DRUG

A total of 7 doses of FEP-ZID via intravenous infusion over 60 min at q8hr dosing regimen

Interventions

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FEP-ZID

A total of 7 doses of FEP-ZID via intravenous infusion over 60 min at q8hr dosing regimen

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Body mass index (BMI) greater than or equal to18.5 and less than or equal to 30 (kg per m2) and weight between 55.0 and 100.0 kg (both inclusive).
* Medical history without any major pathology as judged by the Investigator.
* Forced expiratory volume in 1 second (FEV1) of at least 70% of predicted value at screening.

Exclusion Criteria

* History or presence of significant oncologic, cardiovascular, pulmonary, hepatic, renal, hematological, gastrointestinal,endocrine, immunologic, dermatologic, neurological, or psychiatric disease.
* Positive alcohol breath test or urine drug screen test at screening or confinement.
* Current use or has used tobacco or nicotine containing products 6 month prior to screening.
* Positive testing for HIV, Hepatitis B or Hepatitis C.
* History or presence of alcohol or drug abuse within the 2 years prior to screening.
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Wockhardt

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Pulmonary Associates

Phoenix, Arizona, United States

Site Status

Countries

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United States

Other Identifiers

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W-5222-104

Identifier Type: -

Identifier Source: org_study_id

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