Pessary Satisfaction Criteria for Urogenital Prolapse

NCT ID: NCT03615872

Last Updated: 2024-09-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-06-20

Study Completion Date

2025-06-30

Brief Summary

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Genital prolapse is a common pathology with a prevalence ranging from 2.9 to 11.4% or 31.8% to 97.7%, depending on whether a questionnaire or clinical examination is used. The use of pessary in the treatment of prolapse remains discussed despite a satisfaction rate of 50 to 80% in the literature and a minimal complications rate.

The main objective of this study is to assess the satisfaction of patients carrying a pessary in the first year after the laying.

Detailed Description

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This is a prospective observational cohort conducted at the Universitary hospital of Caen over a total period of 5 years.

Patients with a symptomatic genital prolapse will all be offered the installation of a pessary. If they agree to participate in the study, they will be asked to respond to validated questionnaires: symptom questionnaires (PFDI-20, ICIQ-SF, USP), a sexuality questionnaire (PISQ-12), a quality of life questionnaire (PFIQ-7, BIS) and Satisfaction (PGI-I), several times: Before the installation of the pessary, at one month, at 6 months, then annually over 5 years

Conditions

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Genital Prolapse Pessary Satisfaction

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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pessary use

evaluation of satisfaction of pessary use in case of symptomatic genital prolapse

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* The research protocol will be proposed to all patients with a symptomatic genital prolapse, over 18 years of age, who speak French and who agree to participate in this study
* Prolapse defined according to the International Classification POP-Q-.

Exclusion Criteria

* Minors under 18 years of age
* Pregnant or lactating women
* Women Not speaking French (the good understanding of French is necessary to answer questionnaires and for informed information)
* Women unable to understand due to cognitive impairment or degenerative disease (dementia/ Alzheimer's disease)
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Caen

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Anne Cecile PIZZOFERRATO, MD

Role: PRINCIPAL_INVESTIGATOR

Universitary Hospital of Caen

Locations

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Pizzoferato

Caen, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Anne Cecile PIZZOFERRATO, MD

Role: CONTACT

+33231272723

Anne VILLOT, MD

Role: CONTACT

+33231272336

Facility Contacts

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Anne Cecile Pizzoferrato, MD

Role: primary

+33231272336

References

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Cundiff GW, Amundsen CL, Bent AE, Coates KW, Schaffer JI, Strohbehn K, Handa VL. The PESSRI study: symptom relief outcomes of a randomized crossover trial of the ring and Gellhorn pessaries. Am J Obstet Gynecol. 2007 Apr;196(4):405.e1-8. doi: 10.1016/j.ajog.2007.02.018.

Reference Type BACKGROUND
PMID: 17403437 (View on PubMed)

Clemons JL, Aguilar VC, Tillinghast TA, Jackson ND, Myers DL. Patient satisfaction and changes in prolapse and urinary symptoms in women who were fitted successfully with a pessary for pelvic organ prolapse. Am J Obstet Gynecol. 2004 Apr;190(4):1025-9. doi: 10.1016/j.ajog.2003.10.711.

Reference Type BACKGROUND
PMID: 15118635 (View on PubMed)

Patel M, Mellen C, O'Sullivan DM, LaSala CA. Impact of pessary use on prolapse symptoms, quality of life, and body image. Am J Obstet Gynecol. 2010 May;202(5):499.e1-4. doi: 10.1016/j.ajog.2010.01.019. Epub 2010 Feb 20.

Reference Type BACKGROUND
PMID: 20171608 (View on PubMed)

Lone F, Thakar R, Sultan AH, Karamalis G. A 5-year prospective study of vaginal pessary use for pelvic organ prolapse. Int J Gynaecol Obstet. 2011 Jul;114(1):56-9. doi: 10.1016/j.ijgo.2011.02.006. Epub 2011 May 14.

Reference Type BACKGROUND
PMID: 21575953 (View on PubMed)

Clemons JL, Aguilar VC, Sokol ER, Jackson ND, Myers DL. Patient characteristics that are associated with continued pessary use versus surgery after 1 year. Am J Obstet Gynecol. 2004 Jul;191(1):159-64. doi: 10.1016/j.ajog.2004.04.048.

Reference Type BACKGROUND
PMID: 15295358 (View on PubMed)

Panman CM, Wiegersma M, Kollen BJ, Burger H, Berger MY, Dekker JH. Predictors of unsuccessful pessary fitting in women with prolapse: a cross-sectional study in general practice. Int Urogynecol J. 2017 Feb;28(2):307-313. doi: 10.1007/s00192-016-3107-4. Epub 2016 Aug 15.

Reference Type BACKGROUND
PMID: 27525693 (View on PubMed)

Markle D, Skoczylas L, Goldsmith C, Noblett K. Patient characteristics associated with a successful pessary fitting. Female Pelvic Med Reconstr Surg. 2011 Sep;17(5):249-52. doi: 10.1097/SPV.0b013e31822f00ae.

Reference Type BACKGROUND
PMID: 22453110 (View on PubMed)

Mutone MF, Terry C, Hale DS, Benson JT. Factors which influence the short-term success of pessary management of pelvic organ prolapse. Am J Obstet Gynecol. 2005 Jul;193(1):89-94. doi: 10.1016/j.ajog.2004.12.012.

Reference Type BACKGROUND
PMID: 16021064 (View on PubMed)

Geoffrion R, Zhang T, Lee T, Cundiff GW. Clinical characteristics associated with unsuccessful pessary fitting outcomes. Female Pelvic Med Reconstr Surg. 2013 Nov-Dec;19(6):339-45. doi: 10.1097/SPV.0b013e3182a26174.

Reference Type BACKGROUND
PMID: 24165447 (View on PubMed)

Kuhn A, Bapst D, Stadlmayr W, Vits K, Mueller MD. Sexual and organ function in patients with symptomatic prolapse: are pessaries helpful? Fertil Steril. 2009 May;91(5):1914-8. doi: 10.1016/j.fertnstert.2008.02.142. Epub 2008 Apr 14.

Reference Type BACKGROUND
PMID: 18410935 (View on PubMed)

Jelovsek JE, Barber MD. Women seeking treatment for advanced pelvic organ prolapse have decreased body image and quality of life. Am J Obstet Gynecol. 2006 May;194(5):1455-61. doi: 10.1016/j.ajog.2006.01.060.

Reference Type BACKGROUND
PMID: 16647928 (View on PubMed)

Other Identifiers

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2018-A00004-51

Identifier Type: -

Identifier Source: org_study_id

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