Effects of a Dipeptidyl Peptidase-4 Inhibitor Sitagliptininsulin on the Progression of Coronary Atherosclerosis in Patients With Type 2 Diabetes

NCT ID: NCT03602638

Last Updated: 2018-07-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE4

Total Enrollment

300 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-10-01

Study Completion Date

2020-12-01

Brief Summary

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This study was to investigate the Effect of Sitagliptin, a dipeptidyl peptidase-4 inhibitor, on progression of coronary atherosclerosis in patients with type 2 diabetes.

Detailed Description

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This study was to investigate the Effect of Sitagliptin, a dipeptidyl peptidase-4 inhibitor, on progression of coronary atherosclerosis in patients with type 2 diabetes.

Conditions

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Atherosclerosis Type 2 Diabetes Mellitus Dipeptidyl Peptidase-4 Inhibitor GLP-1

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Sitagliptin

Group Type EXPERIMENTAL

Sitagliptin

Intervention Type DRUG

Sitagliptin 100mg QD

CONTROL

Acarbose

Group Type ACTIVE_COMPARATOR

Acarbose

Intervention Type DRUG

Acarbose

Interventions

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Sitagliptin

Sitagliptin 100mg QD

Intervention Type DRUG

Acarbose

Acarbose

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients \> 18, \< 80 years old, with type 2 diabetes mellitus and coronary heart disease.

Exclusion Criteria

* Allergy or hypersensitivity to any of the drug's components. Severe liver failure, moderate or severe kidney failure Malignant disease. Active infectious disease. Pregnancy or breastfeeding.
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Chinese PLA General Hospital

OTHER

Sponsor Role lead

Responsible Party

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Li Bo

Li Bo

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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LI BO, MD

Role: CONTACT

+86089837330575

Other Identifiers

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ChinaPLAGH_hainan

Identifier Type: -

Identifier Source: org_study_id

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