Advancing Pre-operative Targeting for Deep Brain Stimulation in the Globus Pallidus Internus
NCT ID: NCT03600740
Last Updated: 2021-04-29
Study Results
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View full resultsBasic Information
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TERMINATED
NA
1 participants
INTERVENTIONAL
2018-08-17
2020-05-18
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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GPi DBS
Patients selected to undergo GPi DBS placement will be eligible for enrollment in the study. In addition to standard-of-care tests, subjects will undergo an MRI consisting of the proposed novel imaging protocol prior to placement of DBS. The patient will subsequently undergo standard-of-care therapy for DBS placement. Once the stimulator has been programmed post-operatively, the stimulation parameters and corresponding clinical changes will be collected and used to model the volume of activated tissue. The patient will additionally undergo a follow-up MRI used to localize the electrode within the brain to further localize the volume of activated tissue.
DBS Programming
DBS Programming may be temporarily altered based on imaging data to measure a change in clinical symptoms.
Interventions
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DBS Programming
DBS Programming may be temporarily altered based on imaging data to measure a change in clinical symptoms.
Eligibility Criteria
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Inclusion Criteria
18 Years
ALL
No
Sponsors
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Mayo Clinic
OTHER
Responsible Party
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Erik H. Middlebrooks, M.D.
Assistant Professor, Radiology and Neurosurgery
Principal Investigators
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Erik H Middlebrooks
Role: PRINCIPAL_INVESTIGATOR
Mayo Clinic
Locations
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Mayo Clinic in Arizona
Scottsdale, Arizona, United States
Mayo Clinic in Florida
Jacksonville, Florida, United States
Mayo Clinic in Rochester
Rochester, Minnesota, United States
Countries
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Provided Documents
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Document Type: Study Protocol and Statistical Analysis Plan
Related Links
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Mayo Clinic Clinical Trials
Other Identifiers
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18-002176
Identifier Type: -
Identifier Source: org_study_id
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