Metabolic Effects of Very Low Carbohydrate Ketogenic Diet in Subjects With Severe Obesity
NCT ID: NCT03564002
Last Updated: 2020-03-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
60 participants
OBSERVATIONAL
2016-10-01
2022-12-31
Brief Summary
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A VLCKD is administered for 25 days to 52 morbid obese patients (BMI 44.7±8.3 kg/m², age 49±12.5 years); at baseline and after diet we evaluated: BMI, glyco-lipidic pattern, abdominal ultrasonography (liver steatosis and visceral fat area) and flow-mediated dilation (FMD). In a subgroup of 20 patients we also tested lysosomal acid lipase (LAL)-activity. A group of healthy normal weight subjects (age 43±13, BMI 22.8±2.6 kg/m²) was also included in the study.
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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obese subjects
No interventions assigned to this group
lean subjects
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Kidney, heart or liver failure
18 Years
65 Years
ALL
Yes
Sponsors
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University Of Perugia
OTHER
Responsible Party
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Maria Anastasia Ricci
Principal Investigator
Locations
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University of Perugia
Perugia, , Italy
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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2017-12
Identifier Type: -
Identifier Source: org_study_id
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