3M Cavilon Advanced Skin Protectant for the Prophylaxis of Radiation Dermatitis

NCT ID: NCT03546803

Last Updated: 2019-08-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

14 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-02-19

Study Completion Date

2019-08-12

Brief Summary

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This study observes a liquid skin protectant that is a polymeric-cyanoacrylate solution designed to protect intact or damaged skin due to radiation.

Detailed Description

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Conditions

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Radiation Dermatitis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Cohort A

Head and Neck Patients; Photon or Proton Treatment with product

3M™ Cavilon™ Advanced Skin Protectant

Intervention Type OTHER

liquid skin protectant on skin to protect from radiation dermatitis

Cohort B

Hair/skin fold areas (Axilla, Groin, Perineum); Photon or Proton Treatment with product

3M™ Cavilon™ Advanced Skin Protectant

Intervention Type OTHER

liquid skin protectant on skin to protect from radiation dermatitis

Cohort C

Misc. (per Rad Onc Physician); Photon or Proton Therapy with routine skin care

3M™ Cavilon™ Advanced Skin Protectant

Intervention Type OTHER

liquid skin protectant on skin to protect from radiation dermatitis

Interventions

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3M™ Cavilon™ Advanced Skin Protectant

liquid skin protectant on skin to protect from radiation dermatitis

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age ≥ 18years.
* Patient has initial or recurrent disease
* Undergoing external beam radiotherapy at the Mayo Clinic Rochester campus Note: Patients who are undergoing concurrent chemotherapy are eligible
* Ability to complete questionnaire(s) by themselves or with assistance
* Provide informed written consent
* Willing to consent for photography of radiation field
* Available to return to Mayo Clinic in within 1 week post treatment for assessment (+/- 7 days).
* At risk for developing ≥ grade 2 dermatitis radiation as determined by treating Radiation Oncology clinician
* Biologic effective dose of \>42 Gy10 as calculated using the web site EQD2.com.

Exclusion Criteria

* Unable to provide informed consent
* Patients with active rash, pre-existing dermatitis, lupus or scleroderma within the treatment area that may make skin assessment for the study difficult
* Known history of developing an allergic reaction after using a product containing cyanoacrylate or acrylates
* Subject has a medical condition that in the opinion of the investigator should exclude him/her from participating in the study
* Subject has been enrolled in an investigational study where product was applied to the proposed study site within 30 days of the screening visit
* The skin area affected by radiation requires treatment with a concomitant medication or product (if applicable)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mayo Clinic

OTHER

Sponsor Role lead

Responsible Party

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Ivy A. Petersen, M.D.

Radiation Oncology Consultant

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Mayo Clinic

Rochester, Minnesota, United States

Site Status

Countries

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United States

Related Links

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Other Identifiers

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ROR1603

Identifier Type: OTHER

Identifier Source: secondary_id

17-006813

Identifier Type: -

Identifier Source: org_study_id

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