A Clinical Evaluation of 3M Cavilon Advanced Barrier Film for the Treatment of Incontinence Associated Dermatitis (IAD)

NCT ID: NCT02724449

Last Updated: 2024-12-17

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-08-31

Study Completion Date

2015-02-28

Brief Summary

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The purpose of this study is to obtain information concerning the safety and effective use of a protective barrier film in patients experiencing severe incontinence associated dermatitis.

Detailed Description

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This is an open label, non randomized prospective case series evaluating 3M Cavilon Advanced Barrier Film for the treatment of severe incontinence associated dermatitis (IAD) in the presence or absence of continued fecal or fecal and urinary incontinence. The product will be applied twice a week for a maximum duration of 3 weeks. Subjects will be followed twice a week until healing, for a maximum of 3 weeks or earlier, if discharged from the facility. During the study period, the frequency and intensity of their incontinence will be monitored, twice a week photographic documentation and IAD site assessments will be completed.

Conditions

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Dermatitis

Keywords

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IAD Fecal incontinence

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Cavilon Advanced Barrier Film

Cavilon Advanced Barrier Film applied to areas of IAD

Group Type EXPERIMENTAL

Cavilon Advanced Barrier Film

Intervention Type DEVICE

Cavilon Advanced Barrier Fim's application applied twice a week

Interventions

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Cavilon Advanced Barrier Film

Cavilon Advanced Barrier Fim's application applied twice a week

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Is the subject 18 years of age or older?
2. Is the subject in a facility providing nursing care 24h per day?
3. Does the subject have severe incontinence-associated dermatitis eg breached or denuded skin? The ideal candidate would have denudement present.
4. Is the subject willing to have photos taken of their skin exposed to incontinence and permit use of the photos in potential publications?
5. Is the subject willing to release rights to 3M for use of the photos?
6. Has the subject signed an Institutional Review Board-approved informed consent document and authorized the use and disclosure of protected health information? At NS-LIJ, only subjects who are capable of consenting are eligible to enroll. The study will not include participants with decisional impairment that would render them incapable of informed consent.

18 years or older

Exclusion Criteria

Subjects are excluded from participation in this study if any of the answers to these questions is yes.

1. If female, is the subject pregnant or breast feeding or have they given birth within the 3 weeks preceding the screening visit?
2. Does the subject have a known allergy to acrylates or cyanoacrylate?
3. Does the subject have a current pressure ulcer in the area where the skin is affected by incontinence?
4. Does the subject have an active genital herpes infection?
5. Does the subject have a pre-existing abnormal skin disease on the treatment areas that may affect skin assessment?
6. Does the skin area involved in this study require treatment with a concomitant medication or product?
7. Has the subject been enrolled in any investigational study within 30 days of the Screening Visit?
8. Does the subject have any medical condition that in the opinion of the investigator should exclude him/her from participating in the study?
9. Has the subject received antifungal powders within 24 hours prior to enrollment?
10. Has the subject received cyanoacrylate based skin protectant to the affected areas (such as Marathon) within 72 hours prior to enrollment?
11. Is the facility unwilling to discontinue use for this subject of Dimethicone containing wipes on the area where the investigational device will be applied?
12. Is the facility unwilling to discontinue use for this subject of Chlorhexidine Gluconate wipes on the area where the investigational device will be applied?
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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3M

INDUSTRY

Sponsor Role collaborator

Solventum US LLC

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

References

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Gray M, Beeckman D, Bliss DZ, Fader M, Logan S, Junkin J, Selekof J, Doughty D, Kurz P. Incontinence-associated dermatitis: a comprehensive review and update. J Wound Ostomy Continence Nurs. 2012 Jan-Feb;39(1):61-74. doi: 10.1097/WON.0b013e31823fe246.

Reference Type RESULT
PMID: 22193141 (View on PubMed)

Doughty D, Junkin J, Kurz P, Selekof J, Gray M, Fader M, Bliss DZ, Beeckman D, Logan S. Incontinence-associated dermatitis: consensus statements, evidence-based guidelines for prevention and treatment, and current challenges. J Wound Ostomy Continence Nurs. 2012 May-Jun;39(3):303-15; quiz 316-7. doi: 10.1097/WON.0b013e3182549118.

Reference Type RESULT
PMID: 22572899 (View on PubMed)

Beeckman D, Schoonhoven L, Verhaeghe S, Heyneman A, Defloor T. Prevention and treatment of incontinence-associated dermatitis: literature review. J Adv Nurs. 2009 Jun;65(6):1141-54. doi: 10.1111/j.1365-2648.2009.04986.x. Epub 2009 Apr 3.

Reference Type RESULT
PMID: 19374674 (View on PubMed)

Other Identifiers

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14-348

Identifier Type: -

Identifier Source: org_study_id