HIT in People With Type 1 Diabetes

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

14 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-03-09

Study Completion Date

2017-10-10

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Few people with type 1 diabetes achieve exercise guidelines and many programmes designed to increase physical activity have failed. High-intensity interval training (HIT) has been shown to be a time-efficient alternative to traditional moderate-intensity continuous training (MICT) in various groups without type 1 diabetes. A single bout of HIT does not increase the risk of hypoglycaemia in people with type 1 diabetes. This study aimed to assess whether HIT a safe, effective and time-efficient training strategy to improve cardio-metabolic health and reduce the risk of hypoglycaemia in people with type 1 diabetes.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

HIT on Hypoglycemic Risk in Type 1 Diabetes (T1D)

NCT03598400

Type1diabetes

COMPLETED NA

Home-HIT and Type 1 Diabetes

NCT03545802

Type1diabetes

COMPLETED NA

Compliance to HIT-program at Home With the Use of Technology

NCT03166852

Diabetes Mellitus, Type 2 Exercise Technology

COMPLETED NA

Restoration of Hypoglycemia Awareness With Home-based High Intensity Interval Training

NCT04825366

Type 1 Diabetes Hypoglycemia Unawareness

COMPLETED NA

Influence of Aerobic Exercise and HIIT on Glycemic Control in Adult Men With Type 1 Diabetes (TAILOR/1b)

NCT06080542

Diabetes Mellitus, Type 1

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

This study aimed to investigate whether 1) six weeks of high-intensity interval training (HIT) induces similar improvements in cardio-metabolic health markers as moderate-intensity continuous training (MICT) in people with type 1 diabetes, and 2) whether HIT abolishes acute reductions in plasma glucose observed following MICT sessions. Fourteen sedentary individuals with type 1 diabetes (n=7 per group) completed six weeks of HIT or MICT 3 times per week. Pre- and post-training measurements were made of 24h interstitial glucose profiles (using continuous glucose monitors (CGMS)) and cardio-metabolic health markers (V ̇O2peak, blood lipid profile and aortic pulse wave velocity; aPWV). Capillary blood glucose concentrations were assessed before and after exercise sessions throughout the training programme to investigate changes in blood glucose during exercise in the fed state.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Type1diabetes

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

HIT training

6 weeks of high-intensity interval training (HIT)

Group Type EXPERIMENTAL

HIT

Intervention Type OTHER

Participants completed 6 weeks of HIT

Moderate intensity training

6 weeks of moderate-intensity continuous training (MICT)

Group Type EXPERIMENTAL

MICT

Intervention Type OTHER

Participants completed 6 weeks of MICT

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

HIT

Participants completed 6 weeks of HIT

Intervention Type OTHER

MICT

Participants completed 6 weeks of MICT

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* duration of type 1 diabetes \>6 months
* basal bolus regimen
* no significant history of hyper- or hypoglycaemia (determined from medical history)

Exclusion Criteria

duration of type 1 diabetes \<6 months,

* insulin pump therapy
* significant history of hyper- or hypoglycaemia (determined from medical history)
* obesity (BMI \>30 kg∙m-2)
* pregnancy or planning pregnancy
* uncontrolled hypertension (\>180/100 mmHg)
* angina, autonomic neuropathy
* taking any medication that affects heart rate
* major surgery planned within 6 weeks of the study
* severe nonproliferative
* unstable proliferative retinopathy

Eligible Sex

Accepts Healthy Volunteers

No