Home-HIT and Type 1 Diabetes

NCT ID: NCT03545802

Last Updated: 2021-03-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

11 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-05-20

Study Completion Date

2018-02-13

Brief Summary

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This study aimed to use a multi-disciplinary approach to evaluate a 6-week home-based high-intensity interval training (Home-HIT) intervention in people with type 1 diabetes.

Detailed Description

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This study aimed to use a multi-disciplinary approach to evaluate a home-based high-intensity interval training (Home-HIT) intervention in people with type 1 diabetes.

Eleven individuals with type 1 diabetes (4 men/7 women; age 30±3 years; BMI 27.1±1.2 kg·m-2; V ̇O2peak 32.4±2.1 ml∙kg∙min-1; duration of type 1 diabetes 10±2 years) completed six weeks of Home-HIT. The effect of Home-HIT on V ̇O2peak, blood pressure, insulin dose and glycaemic profile was assessed pre and post-training. Adherence and ability to meet target heart rate (HR) thresholds (compliance) were monitored using a HR monitor and mobile phone application. Change in glycaemia was measured pre, post and 1h post exercise sessions throughout the six-week period. A qualitative online survey was completed post-training.

This is the first study to combine physiological outcomes with a qualitative evaluation of a training intervention in people with type 1 diabetes. Home-HIT resulted in high adherence alongside increased V ̇O2peak and decreased insulin dose. Because Home-HIT is time-efficient and removes barriers to exercise including fear of hypoglycaemia, it may represent an effective strategy to increase exercise participation in people with type 1 diabetes.

Conditions

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Type1diabetes

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Training

6 weeks of home-based high intensity interval training

Group Type EXPERIMENTAL

Home-HIT

Intervention Type BEHAVIORAL

Participants completed 6 weeks of home-based high-intensity interval training 3 times per week

Interventions

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Home-HIT

Participants completed 6 weeks of home-based high-intensity interval training 3 times per week

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* duration of type 1 diabetes \>6 months,
* no significant history of hyper- or hypoglycaemia

Exclusion Criteria

* duration of type 1 diabetes \<6 months,
* significant history of hyper- or hypoglycaemia,
* pregnancy or planning pregnancy,
* uncontrolled hypertension (\>180/100 mmHg),
* angina
* autonomic neuropathy,
* taking any medication that affects heart rate (HR)
* major surgery planned within 6 weeks of the study
* severe nonproliferative
* unstable proliferative retinopathy
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Liverpool John Moores University

OTHER

Sponsor Role lead

Responsible Party

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Sam Shepherd

Lecturer/Senior Lecturer, Principle Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Liverpool John Moores University

Liverpool, Merseyside, United Kingdom

Site Status

Countries

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United Kingdom

References

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Scott SN, Shepherd SO, Andrews RC, Narendran P, Purewal TS, Kinnafick F, Cuthbertson DJ, Atkinson-Goulding S, Noon T, Wagenmakers AJM, Cocks M. A Multidisciplinary Evaluation of a Virtually Supervised Home-Based High-Intensity Interval Training Intervention in People With Type 1 Diabetes. Diabetes Care. 2019 Dec;42(12):2330-2333. doi: 10.2337/dc19-0871. Epub 2019 Sep 17.

Reference Type DERIVED
PMID: 31530660 (View on PubMed)

Other Identifiers

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Home-HIT_T1D

Identifier Type: -

Identifier Source: org_study_id

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