Effect of Laparoscopic Ovarian Drilling on Outcomes of in Vitro Fertilisation in Clomiphene-resistant Women With Polycystic Ovary Syndrome

NCT ID: NCT03527979

Last Updated: 2018-05-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

88 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-03-01

Study Completion Date

2018-09-30

Brief Summary

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the polycystic ovarian syndrome is associated with an ovulation and infertility. recently the laparoscopic ovarian drilling has been used as surgical treatment for ovulation in women with polycystic ovarian syndrome, although its mechanism and outcomes are still unclear. this study is undertaken to evaluate the in vitro fertilisation outcomes in clomiphene-resistant women with PCOS who were treated with LOD.

Detailed Description

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Conditions

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PCOS

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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PCOS women with history of LOD before IVF/ICSI

Group Type ACTIVE_COMPARATOR

IVF/ICSI

Intervention Type PROCEDURE

IVF/ICSI

PCOS women without history of drilling

Group Type ACTIVE_COMPARATOR

IVF/ICSI

Intervention Type PROCEDURE

IVF/ICSI

Interventions

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IVF/ICSI

IVF/ICSI

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* age between 25 and 35
* patients with established PCOS
* history at least one year infertility
* no response to clomiphene citrate for at least three cycles

Exclusion Criteria

* history of previous IVF/ICSI
* chronic disease such as thyroid disorder and DM
* infertility due to sever male factor
* sever endometriosis
* infertility due to uterine factor such as multiple fibroid
* body mass index \> 30
Minimum Eligible Age

25 Years

Maximum Eligible Age

35 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Ain Shams University

OTHER

Sponsor Role lead

Responsible Party

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rabab adel kamal

ob/gyn resident

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Ain Shams university

Cairo, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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rkamal

Identifier Type: -

Identifier Source: org_study_id

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