Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
104 participants
OBSERVATIONAL
2018-06-12
2019-07-17
Brief Summary
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Detailed Description
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To this end, we will compare measured variables, in patients with intracavitary fluid and without intracavitary fluid.
Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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Patients with intracavitary fluid
to evaluate the correlation between the presence of intracavitary fluid during hormonal stimulation for IVF depending on the position of C-section-scar and the presence of an isthmocele, this group patients will have intracavitary fluid.
ultrasound,transvaginal scan
The presence of fluid in the uterine cavity during hormonal stimulation.
Patients without intracavitary fluid
to evaluate the correlation between the presence of intracavitary fluid during hormonal stimulation for IVF depending on the position of C-section-scar and the presence of an isthmocele, in this group patients will not have intracavitary fluid.
ultrasound,transvaginal scan
The presence of fluid in the uterine cavity during hormonal stimulation.
Interventions
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ultrasound,transvaginal scan
The presence of fluid in the uterine cavity during hormonal stimulation.
Eligibility Criteria
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Inclusion Criteria
* Patients performing IVF treatment.
* One or multiple C-sections.
* C-scar region visible during trans-vaginal scan.
Exclusion Criteria
18 Years
45 Years
FEMALE
Yes
Sponsors
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ART Fertility Clinics LLC
OTHER
Responsible Party
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Barbara Lawrenz
Scientific Director
Principal Investigators
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Human Fatemi, MD
Role: PRINCIPAL_INVESTIGATOR
ART Fertility Clinics LLC
Locations
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IVI Middle East Fertility Clinic
Abu Dhabi, , United Arab Emirates
Countries
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References
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Bij de Vaate AJ, Brolmann HA, van der Voet LF, van der Slikke JW, Veersema S, Huirne JA. Ultrasound evaluation of the Cesarean scar: relation between a niche and postmenstrual spotting. Ultrasound Obstet Gynecol. 2011 Jan;37(1):93-9. doi: 10.1002/uog.8864.
Tower AM, Frishman GN. Cesarean scar defects: an underrecognized cause of abnormal uterine bleeding and other gynecologic complications. J Minim Invasive Gynecol. 2013 Sep-Oct;20(5):562-72. doi: 10.1016/j.jmig.2013.03.008. Epub 2013 May 14.
Vervoort AJ, Uittenbogaard LB, Hehenkamp WJ, Brolmann HA, Mol BW, Huirne JA. Why do niches develop in Caesarean uterine scars? Hypotheses on the aetiology of niche development. Hum Reprod. 2015 Dec;30(12):2695-702. doi: 10.1093/humrep/dev240. Epub 2015 Sep 25.
Chien LW, Au HK, Xiao J, Tzeng CR. Fluid accumulation within the uterine cavity reduces pregnancy rates in women undergoing IVF. Hum Reprod. 2002 Feb;17(2):351-6. doi: 10.1093/humrep/17.2.351.
Lawrenz B, Melado L, Garrido N, Coughlan C, Markova D, Fatemi H. Isthmocele and ovarian stimulation for IVF: considerations for a reproductive medicine specialist. Hum Reprod. 2020 Jan 1;35(1):89-99. doi: 10.1093/humrep/dez241.
Related Links
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Rise in number of C-section deliveries.
Other Identifiers
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1802-ABU-018-HF
Identifier Type: -
Identifier Source: org_study_id
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