Introvision for Migraine and Headaches

NCT ID: NCT03507400

Last Updated: 2025-04-18

Study Results

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

72 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-09-20

Study Completion Date

2020-07-19

Brief Summary

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To evaluate the effect of Introvision, a mental and emotional self-regulation-technique developed by Angelika C. Wager, as migraine preventative compared to a waiting list group.

Detailed Description

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Randomized, single-center, waiting-list control group study: Introvision as preventative in Migraine

Randomized, single center, waiting-list group control study to evaluate the effect of Introvison, a mental and emotional self regulation method to reduce headache days in patients with migraine, migraine and tension type headache and chronic migraine. The number of headache days 3 months after completion of the last session of Introvision will be compared with the number of headache days of the waiting list group in the month before the course to learn Introvision.

Conditions

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Migraine Chronic Migraine

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SEQUENTIAL

waiting list control study
Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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non-waiting list group

Intervention: Introvision: mental and emotional self-regulation

Group Type EXPERIMENTAL

Introvision: mental and emotional self-regulation

Intervention Type BEHAVIORAL

Participants learn Introvision

waiting list group

Intervention: Introvision: mental and emotional self-regulation

Introvision is teached to participants of the waiting-list group at least 6 weaks or more after first group

Group Type EXPERIMENTAL

Introvision: mental and emotional self-regulation

Intervention Type BEHAVIORAL

Participants learn Introvision

Interventions

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Introvision: mental and emotional self-regulation

Participants learn Introvision

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Episodic migraine with at least 5 headache days per month, episodic migraine and tension type headache with at least 5 migraine headache days per month, chronic migraine
* Stable prophylactic headache medication
* Stable non-medication headache prophylaxis (sports, relaxation techniques, …)
* Informed consent

Exclusion Criteria

* Other causes of headache, symptomatic headaches
* Other primary headaches such as Cluster headache, trigeminal neuralgia, idiopathic facial pain, new daily persistent headache
* Severe depression (more than 13 points in the Beck Depression inventory fast screen (BDI-FS)
* Drug - or alcohol abuse
* Non-compliance, especially significant missing entries in the headache diaries
* Active psychosis
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Hamburg-Eppendorf

OTHER

Sponsor Role collaborator

Introvision e.V

UNKNOWN

Sponsor Role collaborator

Ludwig-Maximilians - University of Munich

OTHER

Sponsor Role lead

Responsible Party

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Dr. Monika Empl

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Monika Empl, MD

Role: PRINCIPAL_INVESTIGATOR

Department of Neurology, Marchioninistr. 15, 81377 Munich, Germany

Locations

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Hospital of the Ludwig-Maximilians-University

Munich, Bavaria, Germany

Site Status

Countries

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Germany

References

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Empl M, Loser S, Spille P, Rozwadowska A, Ruscheweyh R, Straube A. Effects of Introvision, a self-regulation method with a mindfulness-based perception technique in migraine prevention: a monocentric randomized waiting-list controlled study (IntroMig Study). J Headache Pain. 2023 Nov 3;24(1):146. doi: 10.1186/s10194-023-01684-0.

Reference Type DERIVED
PMID: 37924063 (View on PubMed)

Provided Documents

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Document Type: Study Protocol: Cover letter EC

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Document Type: Study Protocol: EC application

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Document Type: Study Protocol: EC Form

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Document Type: Study Protocol: Study Protocol without Cover letter wo Application wo Form

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Document Type: Statistical Analysis Plan

View Document

Document Type: Informed Consent Form

View Document

Other Identifiers

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IntroMig 632-15

Identifier Type: -

Identifier Source: org_study_id

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