Effect of Hibiscus and Lippia Extract on Blood Pressure

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

51 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-03-26

Study Completion Date

2019-04-15

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Determine if a double-blind, randomized, placebo-controlled clinical intervention, based on a dietetic intervention and physical exercise, supplemented with a polyphenolic extract, decreases blood pressure in hypertensive volunteers.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Study of the Effect of the Combined Extract of Lemon Verbena and Hibiscus on Health Indicators

NCT05906771

Diet, Mediterranean Antioxidant Effect Body Weight +3 more

COMPLETED NA

The Effect of Hibiscus Sabdariffa L. Tea on Blood Pressure

NCT00175110

Hypertension

COMPLETED PHASE1/PHASE2

Hibiscus Sabdariffa Extract Effect on Neuromuscular Performance

NCT05653076

Neuromuscular Performance

UNKNOWN NA

Olive Leaf Extracts in the Control of Hypertension

NCT05636826

Hypertension

RECRUITING PHASE2/PHASE3

Effect of Hibiscus Sabdariffa on Blood Pressure in a University Population

NCT03804801

Elevated Blood Pressure

UNKNOWN PHASE4

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Slightly hypertensive individuals, before diagnosed with type 1 hypertension, are generally monitored by their physician and given dietetic and physical activity guidelines. The objective of this intervention is to prevent onset of a hypertensive pathologic condition. However, in many cases, this intervention is unsuccessful, and therefore the patient must follow-up with anti-hypertensive drugs.

Here, in the current study, the objective is to include a nutritional supplement in the intervention in order to increase the probability of success of the diet/exercise intervention. Previous studies with the supplement Metabolaid has shown the product to significantly decrease the blood pressure of slightly hypertensive individuals. It is estimated, based on the results of previous clinical studies, that the polyphenolic content of the nutritional supplement will reduce at least an additional 10% of the blood pressure of the patients undergoing a diet and exercise intervention.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Blood Pressure

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

TRIPLE

Participants Caregivers Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Placebo Control

2 capsules per day, each with 400 mg Cellulose microcrystalline, for 6 weeks.

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DIETARY_SUPPLEMENT

500 mg per day, in fasting conditions.

Dietetic Supplement Group

2 Capsules per day of Metabolaid® (each capsule contains 250 mg Metabolaid®, 150 mg cellulose microcrystalline), for 6 weeks.

Group Type EXPERIMENTAL

Metabolaid®

Intervention Type DIETARY_SUPPLEMENT

500 mg per day, in fasting conditions.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Metabolaid®

500 mg per day, in fasting conditions.

Intervention Type DIETARY_SUPPLEMENT

Placebo

500 mg per day, in fasting conditions.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Slight or type 1 hypertension with no pharmacological treatment, but with annual controls of the blood pressure

Exclusion Criteria

* Minors (under 18 years of age)
* volunteers with high cardiovascular disease risk
* pharmacological treatment for blood pressure
* presence of any chronic disease/condition
* known allergies regarding the supplement and/or placebo

Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes