Effect of Oral Collagen Tripeptide on Skin Moisture and Wrinkles in Adult Women

NCT ID: NCT03505684

Last Updated: 2018-08-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

84 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-12-24

Study Completion Date

2018-07-30

Brief Summary

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Comparison of a randomized, double-blind, and control-group study for the effect of oral ingestion of collagen tripeptides derived from fish on dermal moistures and wrinkles body fat reduction in participants

Detailed Description

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The aim is to investigate the effect of oral ingestion of collagen tripeptides derived from fish on dermal moistures and wrinkles body fat reduction in participants by a randomized, double-blind, and control-group study.

Conditions

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Skin Manifestations Skin Wrinkling

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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CTP group

1,000 mg of collagen tripeptide (CTP) was orally administered per day for 12 weeks.

Group Type EXPERIMENTAL

CTP

Intervention Type DIETARY_SUPPLEMENT

1,000 mg of CTP was orally administered per day for 12 weeks.

Control group

1,000 mg of placebo (starch) was orally administered per day for 12 weeks

Group Type PLACEBO_COMPARATOR

placebo (starch)

Intervention Type DIETARY_SUPPLEMENT

placebo (starch)

Interventions

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CTP

1,000 mg of CTP was orally administered per day for 12 weeks.

Intervention Type DIETARY_SUPPLEMENT

placebo (starch)

placebo (starch)

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

\- \> = 4 of Tewameter

Exclusion Criteria

* Within the last 6 months, took skin surgery including cosmetic purpose
* Diabetic patients with poor glycemic control with a fasting blood glucose of 160 mg/dl or more
* Creatinine levels: more than twice the normal upper limit
* AST (GOT) or ALT (GPT) levels: more than twice the normal upper limit
* Uncontrolled hypertension
* sun allergy or sensitive skin
* functional cosmetics that affect dermal moistures and wrinkles within the last 3 months.
* If you have participated or are planning to participate in another clinical trial within the past month
* Alcohol abuser
* If they are pregnant or lactating or have a pregnancy plan during the clinical trial Those with allergic reactions to the constituent food
* Any person deemed inappropriate by the researcher for other reasons
Minimum Eligible Age

40 Years

Maximum Eligible Age

60 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Pusan National University Yangsan Hospital

OTHER

Sponsor Role lead

Responsible Party

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Sang Yeoup Lee

Principal Investigator, Professor, Head of Integrated Research Institute for Natural Ingredients and Functional Foods (IRINIF)

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Sang Yeoup Lee, MD

Role: PRINCIPAL_INVESTIGATOR

Integrated Research Institute for Natural Ingredients and Functional Foods

Locations

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Integrated Research Institute for Natural Ingredients and Functional Foods

Yangsan, , South Korea

Site Status

Countries

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South Korea

References

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Tak YJ, Shin DK, Kim AH, Kim JI, Lee YL, Ko HC, Kim YW, Lee SY. Effect of Collagen Tripeptide and Adjusting for Climate Change on Skin Hydration in Middle-Aged Women: A Randomized, Double-Blind, Placebo-Controlled Trial. Front Med (Lausanne). 2021 Jan 11;7:608903. doi: 10.3389/fmed.2020.608903. eCollection 2020.

Reference Type DERIVED
PMID: 33521019 (View on PubMed)

Other Identifiers

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02-2017-033

Identifier Type: -

Identifier Source: org_study_id

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