A Novel Urinary Access System for Universal Transcatheter Cystoscopy at The Time of Hysterectomy

NCT ID: NCT03503175

Last Updated: 2020-07-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

364 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-07-26

Study Completion Date

2022-03-01

Brief Summary

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Cystoscopy is a commonly performed procedure after gynecologic surgery, however, its use may increase patients' risk for acquiring urinary tract infections due to urinary tract instrumentation entry and reentry of the lower urinary tract with the cystoscope and foley catheter. Use of a novel multi-channel transurethral bladder catheter that allows for cystoscopy through a specialized port will permit cystoscopy to be performed without catheter removal. This may allow for intraoperative detection of urinary tract injuries with a reduction in both urethral manipulation and hospital-associated urinary tract infections. Other potential benefits may include a shorter procedure time and ease of use for providers.

Detailed Description

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A cystoscopy is a procedure that inserts a thin tube with a light and camera through the urethra, so that the inside of the bladder can be checked for injuries. Current guidelines recommend that this is done after a hysterectomy. Normally, doing a cystoscopy requires that a patient's foley catheter (a tube inserted through the urethra and into the bladder to drain urine) gets removed and then replaced. This can potentially lead to a urinary tract infection (UTI).

CystoSureTM is a silicone device that was developed by surgeons to enable easy and standardized cystoscopy. The design of the CystoSureTM catheter has separate channels for draining the bladder and performing cystoscopy, so doctors can perform a cystoscopy without removing the catheter (which can, as described above, potentially lead to a UTI). In this study, investigators want to examine whether using a CystoSureTM catheter instead of a standard foley catheter could therefore lead to a reduced number of UTIs in hysterectomy patients. CystoSureTM is cleared by the FDA.

Conditions

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Hysterectomy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Novel urinary access system

Participants randomized to this arm will receive the novel urinary access system (CystoSureTM).

Group Type EXPERIMENTAL

Novel urinary access system (CystoSureTM)

Intervention Type DEVICE

CystoSureTM is a silicone device that was developed by surgeons to enable easy and standardized cystoscopy. The design of the CystoSureTM catheter has separate channels for draining the bladder and performing cystoscopy, so doctors can perform a cystoscopy without removing the catheter (which can, as described above, potentially lead to a UTI).

Standard Foley catheter

Participants randomized to this arm will receive a standard Foley catheter and rigid cystoscopy.

Group Type ACTIVE_COMPARATOR

Standard Foley catheter

Intervention Type DEVICE

Participants randomized to this arm will receive a standard Foley catheter and standard rigid cystoscopy.

Interventions

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Novel urinary access system (CystoSureTM)

CystoSureTM is a silicone device that was developed by surgeons to enable easy and standardized cystoscopy. The design of the CystoSureTM catheter has separate channels for draining the bladder and performing cystoscopy, so doctors can perform a cystoscopy without removing the catheter (which can, as described above, potentially lead to a UTI).

Intervention Type DEVICE

Standard Foley catheter

Participants randomized to this arm will receive a standard Foley catheter and standard rigid cystoscopy.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Women age 18-90
* Undergoing hysterectomy with or without concomitant procedures

Exclusion Criteria

* Known history of urinary tract anomaly (i.e. urethral diverticulum, ureteral duplication, ectopic ureter)
* ≥3 UTIs in past 6 months
* Immunosuppressed patients
* Premeditated urologic procedure during hysterectomy surgery
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Atlantic Health System

OTHER

Sponsor Role lead

Responsible Party

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charbel salamon

Principal Investigator; Director, Urogynecology

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Atlantic Urogynecology Associates

Morristown, New Jersey, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Caroline Sabatino, MPH, CCRP

Role: CONTACT

973-971-7361

Charbel Salamon, MD, MS

Role: CONTACT

973-971-7267

Facility Contacts

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Caroline Sabatino, MPH, CCRP

Role: primary

973-971-7361

Other Identifiers

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1178748

Identifier Type: -

Identifier Source: org_study_id

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