Neopterin Dosage in the Eye

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-06-22

Study Completion Date

2019-01-25

Brief Summary

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The purpose of the study is to determine whether neopterin can be dosed in the fluid of the eye's anterior chamber for patient with non-inflammatory and non-infectious ophthalmic pathology.

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Detailed Description

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The study will be explained to subjects who are about to undergo ophthalmologic surgery. They will sign an informed consent and be included in the study. Urine sample will be collected specifically for the study. Eye's anterior chamber fluid will also be collected during the surgery as it is the usual practice (the sample is used for the neopterin dosage instead of being thrown away).

These samples will be centrifuged, frozen in a -80° C freezer. At the end of the study, all the samples will be sent to the central Lab for the neopterin dosage analysis. Results will be communicated to the principal investigator afterward.

Conditions

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Cataract

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Neopterin Dosage

Eye's anterior chamber fluid and urines are sampled for posterior neopterin analysis

Samples

Intervention Type BIOLOGICAL

Eye's anterior chamber fluid and urines are sampled for posterior neopterin analysis

Interventions

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Samples

Eye's anterior chamber fluid and urines are sampled for posterior neopterin analysis

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

* Age ≥ 18 years-old
* Non inflammatory or non infectious ophthalmic pathology requiring puncture of eye's anterior chamber fluid.
* Minimum of 200 microliter sample
* Immunocompetent subjects
* Signed and dated informed consent
* Samples management in accordance with the pre-analytical conditions specified in the protocol

* Age \< 18 years-old
* Subjects treated with intraocular corticoids, antibiotics or anti-inflammatory, locally or in systemic injection, prior to inclusion.

Exclusion Criteria

* Subjects who exercised his right of withdrawal
* Study suspended on principal investigator, sponsor or health authorities' demand.
* Deceased subjects

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No