Efficacy Evaluation of SYSTANE® ULTRA in Patients Scheduled for Cataract Surgery

NCT ID: NCT01199510

Last Updated: 2016-11-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-09-30

Study Completion Date

2011-06-30

Brief Summary

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The purpose of this study is to evaluate the effectiveness of FID 112903 (SYSTANE ULTRA® Lubricating Drops) plus standard of care to standard of care alone, in subjects with a history of intermittent eye irritation or dryness related to environmental factors and scheduled for routine cataract surgery.

Detailed Description

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Conditions

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Dry Eye Cataract Surgery

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

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Standard of Care plus FID 112903

SYSTANE® ULTRA Lubricant Eye Drops dosed 4 times daily

Group Type EXPERIMENTAL

FID 112903 (SYSTANE® ULTRA Lubricant Eye Drops) plus standard of care

Intervention Type OTHER

Patients will dose 4 times daily for 30 days with FID 112903 and follow routine standard of care post-operatively

Standard of Care only

Post Cataract Standard of Care Regimen

Group Type ACTIVE_COMPARATOR

Standard of Care

Intervention Type OTHER

Post Cataract Surgery Standard of Care

Interventions

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FID 112903 (SYSTANE® ULTRA Lubricant Eye Drops) plus standard of care

Patients will dose 4 times daily for 30 days with FID 112903 and follow routine standard of care post-operatively

Intervention Type OTHER

Standard of Care

Post Cataract Surgery Standard of Care

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients must be at least 18 years of age
* Patients must be seeking routine cataract extraction with monofocal intraocular lens implantation

* Patients cannot have a history of hypersensitivity to any component of FID 112903.
* Patients cannot have previous intraocular or corneal surgery or any planned within 30 days.
* Patients cannot use any ocular medications other than test article and standard of care post-op medications in past 14 days or during study.
* Patients cannot be on chronic systemic corticosteroid or other immunosuppressive therapy.
* Patients cannot have a history of steroid-responsive rise in intraocular pressure, glaucoma, or preoperative Intraocular pressure \>25 millimeters mercury in either eye.
* Patients cannot have a history and/or current evidence of the following: clinically significant corneal scarring, blepharitis or macular pathology in either eye, Herpes zoster or Herpes simplex keratitis.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Alcon Research

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Countries

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United States

References

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http://www.escrs.org/abstracts/details.asp?confid=9&sessid=372&type=free&paperid=14295

Reference Type RESULT

Other Identifiers

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SMA-09-05

Identifier Type: -

Identifier Source: org_study_id