Statin Eligibility Prior to Myocardial InfarCtion

NCT ID: NCT03485742

Last Updated: 2019-06-26

Basic Information

• Recruitment Status: TERMINATED
• Total Enrollment: 740 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2019-04-22
• Study Completion Date: 2019-06-10

Brief Summary

The study (Statin Eligibility Prior to myocardial infarction (MI) in Jordanians, StatinEPIC) is

1. Cross sectional

2. Non interventional

3. One encounter per patient. No follow up. It addresses a major issue of primary prevention in Jordanians especially the young population, namely the issue of lipid lowering agents before sustaining an acute MI. A recent study in USA showed that 50% of patients who sustained MI were not eligible to statins had they been evaluated before the heart attack. It is largely unknown if a larger percentage of Middle Eastern patients who sustain a heart attack would be eligible to receive lipid lowering agents.

4. The PI will overlook the whole process. Dr Ahmad Tamari, the assistant to the PI will asses this whole process of data collection, management and manuscript drafting.

Detailed Description

Statins, when use as primary cardiovascular prevention strategy, have been shown to lower future acute cardiovascular events, especially myocardial infarction. However the use of statins in this context (i.e., primary prevention) is governed by guidelines that limit the use of statins to four high risk populations: (1) hose with known cardiovascular disease, (2) those with low-density lipoprotein cholesterol (LDL-C) levels 190 mg/dl or above, (3) diabetics with LDL-C levels 70-189 mg/dl, and (4) those with an estimated 10-year atherosclerotic cardiovascular disease risk score of 7.5% or more.

Unfortunately, some individuals are still at risk of sustaining MI despite the fact that they do not fit into one of these four high risk groups eligible for statins.

StainEPIC will enroll consecutive patients admitted with MI who are not on statins to examine their eligibility for these medications based on the AHA/ACC guidelines.

Conditions

Statins; Myocardial Infarction

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: CROSS_SECTIONAL

Interventions

No intervention

No intervention. Collection of data on statin eligibility in patients admitted with MI

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Adults admitted with MI, age 30 to 75
• known lipid profile

Exclusion Criteria

• on statin before enrollment

• Minimum Eligible Age: 30 Years
• Maximum Eligible Age: 75 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Jordan Collaborating Cardiology Group

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Yasmine Obeidat, MS

Role: STUDY_DIRECTOR

Hashemmeyyeh University School of Medicine, Zarka, Jordan

Ayman J Hammoudeh, MD, FACC

Role: PRINCIPAL_INVESTIGATOR

Istishari Hospital, Department of Cardiology, Amman, Jordan

Locations

Istishari Hospital

Amman, , Jordan

The University of Jordan

Amman, , Jordan

Jordan Hospital

Amman, , Jordan

Khalidi Hospital & Medical Center

Amman, , Jordan

King Abdullah University Hospital

Irbid, , Jordan

Countries

Jordan

Other Identifiers

JCCStatinEpic2018

Identifier Type: -

Identifier Source: org_study_id