Comparison of Two Volar Plating Systems for Distal Radius Fractures

NCT ID: NCT03474445

Last Updated: 2022-04-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

106 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-03-01

Study Completion Date

2022-02-28

Brief Summary

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We plan to compare 2 types of plating systems for volar plating of distal radius fractures (Aptus 2.5® Medartis AG, Basel, Switzerland vs. INTEOS 2.5® - Hofer Medical GmbH and Co KG, Austria) in a prospective single-blinded controlled clinical trial.

Detailed Description

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This study represents a prospective randomized clinical trial comparing two different systems of volar plate osteosynthesis in patients with distal radius fractures.

Patients meeting the inclusion criteria will be enrolled in the present study provided they give their consent. Informed written consent will be obtained. Envelopes will be prepared containing equal number of cards representing either the conventional or the novel plating syste. On the morning of the surgery a randomly picked envelope decides allocation one of the study groups. Patients will be blinded to treatment until completion of the study. Patients allocated to the control group receive Aptus 2.5® volar plate for distal radius fractures (Medartis AG, Basel, Switzerland), while patients in the study group will receive the plating system INTEOS 2.5® (Hofer GmbH and Co KG, Austria). In the control group, the pronator quadratus muscle will be cut prior mounting of the plate, while in the treatment group the plate will be inserted underneath the pronator quadratus leaving the muscle intact.

Conditions

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Distal Radius Fracture

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Control group

Volar Plate Osteosynthesis Aptus 2.5

Group Type ACTIVE_COMPARATOR

Volar Plate Osteosynthesis Aptus 2.5

Intervention Type PROCEDURE

Volar plating of distal radius fracture. Device: Aptus 2.5

Study Group

Volar Plate Osteosynthesis Inteos 2.5

Group Type ACTIVE_COMPARATOR

Volar Plate Osteosynthesis Inteos 2.5

Intervention Type PROCEDURE

Volar plating of distal radius fracture. Device: Inteos 2.5

Interventions

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Volar Plate Osteosynthesis Aptus 2.5

Volar plating of distal radius fracture. Device: Aptus 2.5

Intervention Type PROCEDURE

Volar Plate Osteosynthesis Inteos 2.5

Volar plating of distal radius fracture. Device: Inteos 2.5

Intervention Type PROCEDURE

Other Intervention Names

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Henry approach, cutting of pronator quadratus Henry approach, preservation of pronator quadratus

Eligibility Criteria

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Inclusion Criteria

* " Distal radius fracture, Type A2, A3, B1, B2, B3, C1, C2 (according to AO Müller classification3) " Patient age between 18 and 75 years " Closed fracture or I° open fractures (according to Gustilo-Anderson classification6) " Agreement of patient to participate and written informed consent

Exclusion Criteria

* " Polytraumatized patients " Severe systemic disorder (ASA 3) " New and/or preexisting fracture/Injury of contralateral forearm " II° and III° open fractures (according to Gustilo-Anderson classification6) " Associated injuries of the ipsilateral wrist (e.g. scapholunate dissociation, concomitant fractures) " Non-compliance to postoperative protocol (e.g. physiotherapy) " Delayed definitive surgical treatment of more than 14 days after injury " Change from temporary procedure (e.g. Fixateur externe) " Complex regional pain syndrome (CRPS, M.Sudeck) " Loss to follow-up
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medical University of Vienna

OTHER

Sponsor Role lead

Responsible Party

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Thomas Haider

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Thomas Haider, M.D., Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Medical University of Vienna

Locations

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Medical Universtiy of Vienna

Vienna, , Austria

Site Status

Countries

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Austria

References

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Thalhammer G, Hruby LA, Dangl T, Liebe J, Erhart J, Haider T. Does the pronator-sparing approach improve functional outcome, compared to a standard volar approach, in volar plating of distal radius fractures? A prospective, randomized controlled trial. J Orthop Traumatol. 2023 Apr 28;24(1):16. doi: 10.1186/s10195-023-00700-y.

Reference Type DERIVED
PMID: 37118158 (View on PubMed)

Other Identifiers

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2339/2016

Identifier Type: -

Identifier Source: org_study_id

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