Pre-phase Treatment Before R-CHOP Chemotherapy in Elderly Patients With Newly Diagnosed DLBCL
NCT ID: NCT03465527
Last Updated: 2022-04-01
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE2
37 participants
INTERVENTIONAL
2017-04-13
2021-07-13
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
SUPPORTIVE_CARE
NONE
Study Groups
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Prednisolone
Prednisolone 50mg bid po or iv (equivalent dose of other steroid) for 5 days ± 2 days
Hydration, antibiotics, allopurinol, nutritional supplements, and so on.
PrednisoLONE 50 MG
Prednisolone 50mg bid po or iv (equivalent dose of other steroid) for 5 days ± 2 days
Interventions
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PrednisoLONE 50 MG
Prednisolone 50mg bid po or iv (equivalent dose of other steroid) for 5 days ± 2 days
Eligibility Criteria
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Inclusion Criteria
2. Diagnosis time 65 years old or older
3. Patients planning R-CHOP chemotherapy
4. Ann Arbor stage 2 (bulky ≥ diameter of 7cm), stage 3 or stage 4
5. The International Prognostic Index (IPI) is a high intermediate or high risk
6. Patients without prior history of lymphoma
7. The decision to participate voluntarily in this study and the written consent of the patient
Exclusion Criteria
2. Large B-cell lymphoma involving the central nervous system
3. Inadequate systemic disease A. Patients with clinically significant heart disease (congestive heart failure, symptomatic coronary artery disease, cardiac arrhythmia) or myocardial infarction within the past 6 months B. Serious neurological and psychiatric illness C. Serious active infection D. Other medical illnesses other than clinical trials
4. If the drug used in this study is allergic
5. If you do not agree to participate in the study
65 Years
ALL
No
Sponsors
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Kosin University Gospel Hospital
OTHER
Responsible Party
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Ho Sup Lee
MD, PhD. associate professor, Division of hematology-Oncology
Locations
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Kosin University Gospel Hospital
Busan, Sue-gu, South Korea
Countries
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Other Identifiers
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Prephase
Identifier Type: -
Identifier Source: org_study_id
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