The Role of Microbiota on the Development of Lung Cancer

NCT ID: NCT03454685

Last Updated: 2019-06-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-01-30

Study Completion Date

2020-03-30

Brief Summary

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Relationship between human microbiota and epidemiology of lung cancer

Detailed Description

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In this study,We aim to find some kinds of human microbiota , which were associated with development of non-small cell lung cancer.

Conditions

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NSCLC, Stage I NSCLC, Stage II NSCLC, Stage III NSCLC Stage IV Healthy Subjects

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

OTHER

Study Groups

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NCSLC group

NSCLC patients,including stage I to stage IV.

without intervention type

Intervention Type OTHER

Without intervention,this study is just an observational study.

Healthy subjects

healthy subjects

without intervention type

Intervention Type OTHER

Without intervention,this study is just an observational study.

Interventions

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without intervention type

Without intervention,this study is just an observational study.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* non-small cell lung cancer patients

Exclusion Criteria

* long-term workers in the polluted environment, Patients who had used antibiotics within 1 month before sampling,
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Xiaorong Dong

OTHER

Sponsor Role lead

Responsible Party

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Xiaorong Dong

Professor

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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dong xiaorong, Dr

Role: STUDY_DIRECTOR

china government

Locations

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Union hospital

Wuhan, Hubei, China

Site Status RECRUITING

Countries

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China

Central Contacts

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dong xiaorong, Dr

Role: CONTACT

15071116896

Facility Contacts

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dong xiaorong, Dr

Role: primary

References

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Lu H, Gao NL, Tong F, Wang J, Li H, Zhang R, Ma H, Yang N, Zhang Y, Wang Y, Liang Z, Zeng H, Chen WH, Dong X. Alterations of the Human Lung and Gut Microbiomes in Non-Small Cell Lung Carcinomas and Distant Metastasis. Microbiol Spectr. 2021 Dec 22;9(3):e0080221. doi: 10.1128/Spectrum.00802-21. Epub 2021 Nov 17.

Reference Type DERIVED
PMID: 34787462 (View on PubMed)

Other Identifiers

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745435

Identifier Type: -

Identifier Source: org_study_id

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