Study of Nivolumab for Advanced Cancers in India

NCT ID: NCT03444766

Last Updated: 2020-12-04

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-03-06

Study Completion Date

2019-07-17

Brief Summary

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This is a study of nivolumab in participants with advanced Non-Small Cell Lung Cancer or Kidney Cancer in India.

Detailed Description

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Conditions

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Non-Small Cell Lung Cancer (NSCLC) Non-Small-Cell Lung Carcinoma Nonsmall Cell Lung Cancer Kidney Cancer Kidney Neoplasms Renal Cancer Renal Neoplasms

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Monotherapy

administering nivolumab only

Group Type EXPERIMENTAL

Nivolumab

Intervention Type DRUG

specified dose on specified days

Interventions

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Nivolumab

specified dose on specified days

Intervention Type DRUG

Other Intervention Names

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Opdivo

Eligibility Criteria

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Inclusion Criteria

* Locally advanced or metastatic non-small cell lung cancer (NSCLC) after prior chemotherapy OR advanced renal cell carcinoma (RCC) after prior therapy
* Eastern Cooperative Oncology Group (ECOG) performance status of ≤ 1
* Prior radiotherapy or radiosurgery must have been completed at least 2 weeks prior to randomization

Exclusion Criteria

* Participants with untreated, symptomatic central nervous system (CNS) metastases
* Participants with carcinomatous meningitis
* Participants with active, known or suspected autoimmune disease
* Participants with a condition requiring systemic treatment with either corticosteroids or other immunosuppressive medications
* Other active malignancy requiring concurrent intervention
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Bristol-Myers Squibb

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Bristol-Myers Squibb

Role: STUDY_DIRECTOR

Bristol-Myers Squibb

Locations

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Local Institution

Bangalore, , India

Site Status

Local Institution

Bangalore, , India

Site Status

Local Institution

Bengaluru, , India

Site Status

Local Institution

Hyderabad, , India

Site Status

Local Institution

Jaipur, , India

Site Status

Local Institution

Kolkata, , India

Site Status

Local Institution

Mumbai, , India

Site Status

Local Institution

New Delhi, , India

Site Status

Local Institution

Vellore, , India

Site Status

Countries

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India

Provided Documents

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Document Type: Statistical Analysis Plan

View Document

Document Type: Study Protocol

View Document

Related Links

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Other Identifiers

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CA209-887

Identifier Type: -

Identifier Source: org_study_id