Salivary Antioxidant Capacity Before and After Complete Dental Rehabilitation
NCT ID: NCT03432728
Last Updated: 2018-02-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
40 participants
OBSERVATIONAL
2016-01-25
2017-12-31
Brief Summary
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Detailed Description
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Aim: This study aimed to measure the salivary TAC levels in children with early childhood caries before and after dental treatment and compare the results to caries free children.
Methodology: Salivary samples were obtained from 20 children in their fifth year of life diagnosed S-ECC and 20 age and gendersex matched controls. Complete dental rehabilitation under general anesthesia was performed for the 20 children with S-ECC, and follow up salivary samples were obtained one week and three months post operatively. The TAC was measured using a commercially available Oxygen Radical Absorbance Antioxidant Assay measurement kit (Zen-Bio ORAC™, AMS Biotechnology, Abington UK).
Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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S-ECC
Children in their fifth year of life with severe early childhood caries Children selected will require complete dental rehabilitation under general anesthesia All enrolled children will receive treatment of all dental carious lesions under general anesthesia
Dental rehabilitation under general anesthesia
Dental treatment of all teeth affected by dental caries in a single visit under general anesthesia
Control
Children age and sex matched with the S-ECC group who are free of dental caries
No interventions assigned to this group
Interventions
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Dental rehabilitation under general anesthesia
Dental treatment of all teeth affected by dental caries in a single visit under general anesthesia
Eligibility Criteria
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Inclusion Criteria
* Age below 71 months
* Test group - to be diagnosed with severe ECC
* Control group - to be caries free
60 Months
72 Months
ALL
Yes
Sponsors
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Riyadh Colleges of Dentistry and Pharmacy
OTHER
Responsible Party
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Dr Sharat Pani
Program Director - Pediatric Dentistry
Principal Investigators
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Sharat C Pani, MDS
Role: PRINCIPAL_INVESTIGATOR
Riyadh Colleges of Dentistry and Pharmacy
Locations
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Riyadh Colleges of Dentistry and Pharmacy
Riyadh, , Saudi Arabia
Countries
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Other Identifiers
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FPGRP/ /43435005/126
Identifier Type: -
Identifier Source: org_study_id
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