The Effect of Periodontal Treatment on the Level of Free Radicals in the Saliva

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-07-31

Brief Summary

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This study will examine the relationship between free radicals in the saliva and periodontitis. 30 adults, 15 with periodontitis and 15 as a control group will give a sample of saliva before treatment and after treatment. The investigators will examine the free radicals in both groups.

Detailed Description

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Periodontal disease is a chronic adult condition. Bacteria implicated in the etiology of this disease causes destruction of connective tissue and bone. As a result of stimulation by bacterial antigen PMN produces free radicals via respiratory burst as a part of host response to infection.

Free radicals can be defined as molecules or molecular fragments with an unpaired electron which imparts certain characteristics to the free radicals such as reactivity . Reactive free radicals are able to produce chemical modifications and to damage proteins, lipids, carbohydrates and nucleotides in the tissues.

Conditions

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Periodontitis

Keywords

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saliva free-radicals periodontitis

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* older than 18
* no medical problems

Exclusion Criteria

* medical problems

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Responsible Party

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the department of oral and maxillofacial surgery - poria madical center

Principal Investigators

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eran front, Dr.

Role: PRINCIPAL_INVESTIGATOR

department of oral and maxillofacial surgery

Locations

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department of oral and maxillofacial surgery, Baruch Padeh Medical Center

Tieberia, Israel, Poria, Israel

Site Status RECRUITING

Countries

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Israel

Facility Contacts

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Eran Front, Dr. DMD

Role: primary

reem younis, Dr.

Role: backup

Other Identifiers

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920090018-YR.ctil

Identifier Type: -

Identifier Source: org_study_id