Greek NIS Spiolto ELLACTO

NCT ID: NCT03419962

Last Updated: 2020-04-27

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1360 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-03-19

Study Completion Date

2019-04-03

Brief Summary

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Open-label observational study: including COPD patients receiving treatment with Spiolto® Respimat® for approximately 6 weeks, which is the average time between two medical consultations

Detailed Description

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Conditions

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Pulmonary Disease, Chronic Obstructive

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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COPD patients

Chronic obstructive pulmonary disease

MaxSpiolto® Respimat® 160 Characters...

Intervention Type DRUG

as per the approved SmPC

Interventions

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MaxSpiolto® Respimat® 160 Characters...

as per the approved SmPC

Intervention Type DRUG

Other Intervention Names

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INSPIOLTO, SPIOLTO, STIOLTO, VAHELVA, YANIMO

Eligibility Criteria

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Inclusion Criteria

* Therapeutic indication before entering the enrollment face is patients diagnosed with COPD requiring a combination therapy of two long-acting bronchodilators (LAMA + LABA) according to approved SmPC and guidelines, COPD GOLD 2017 groups B to D
* Female and male patients ≥40 years of age
* Treatment with Spiolto ® Respimat® acc. to SmPC and at the discretion of the physician
* Written informed consent prior to participation

Exclusion Criteria

* Patients with contraindications according to Spiolto® Respimat® SmPC
* Patients who have been treated with a LABA/LAMA combination (free and fixed dose) in the previous 6 weeks or patients already on a combination of LAMA and LABA therapy; either as a fixed combination product or as separate components Note: Patients previously treated with LABA or LAMA (with or without ICS) are eligible to be included in the study
* Patients continuing LABA-ICS treatment should not be additionally treated with Spiolto® Respimat® in order to avoid a double dosing of long-acting beta-agonists
* Patients for whom further follow-up is not possible at the enrolling site during the planned study period of approx. 6 weeks
* Pregnancy and lactation
* Patients currently listed for lung transplantation
* Current participation in any clinical trial or any other non-interventional study of a drug or device
Minimum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Boehringer Ingelheim

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Metropolitan

Aegina, , Greece

Site Status

Metroplitan

Athens, , Greece

Site Status

Metropolitan

Athens, , Greece

Site Status

Metropolitan

Chania, , Greece

Site Status

Metropolitan

Heraklio, , Greece

Site Status

Metropolitan

Hrakleio, , Greece

Site Status

Metropolitan

Hraklio, , Greece

Site Status

Diavalkaniko

Ioannina, , Greece

Site Status

Diavalkaniko

Kavala, , Greece

Site Status

Diavalkaniko

Larissa, , Greece

Site Status

Metropolitan

Pátrai, , Greece

Site Status

Diavalkaniko

Serres, , Greece

Site Status

Merkouropoulos Markos

Thessaloniki, , Greece

Site Status

Diavalkaniko

Thessaloniki, , Greece

Site Status

Diavalkaniko

Volos, , Greece

Site Status

Countries

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Greece

References

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Kosmas E, Titopoulos I, Patentalakis G, Nikas N. An Observational Study Assessing Changes in Health and Functional Status in Patients with Chronic Obstructive Pulmonary Disease (COPD) During Therapy with Spiolto(R) Respimat(R) in Everyday Clinical Practice: The Greek ELLACTO Study. Pulm Ther. 2021 Dec;7(2):429-443. doi: 10.1007/s41030-021-00156-7. Epub 2021 May 3.

Reference Type DERIVED
PMID: 33939158 (View on PubMed)

Provided Documents

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Document Type: Study Protocol

View Document

Document Type: Statistical Analysis Plan

View Document

Other Identifiers

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1237-0073

Identifier Type: -

Identifier Source: org_study_id

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