Effects of Cardiorespiratory Rehabilitation on the Right Ventricle in Pulmonary Hypertension

NCT ID: NCT03404492

Last Updated: 2023-08-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

12 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-06-12

Study Completion Date

2020-07-05

Brief Summary

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Clinical improvement has been demonstrated after cardiorespiratory rehabilitation in patients with pulmonary hypertension. Rehabilitation is therefore now part of the recommendations for good practice. However, no data is available to elucidate the mechanism of this improvement: an improvement in myocardial reserve or an improvement in peripheral muscular capacity? The main objective of this study is to evaluate the difference in right ventricular contractile reserve before and after cardiorespiratory rehabilitation during stress ultrasound in pulmonary hypertension in 10 patients with pulmonary hypertension.

Detailed Description

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Conditions

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Pulmonary Hypertension

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Patients with pulmonary hypertension

Group Type OTHER

Stress echocardiography

Intervention Type OTHER

A stress echocardiography will be performed in addition to the traditional patient care

Interventions

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Stress echocardiography

A stress echocardiography will be performed in addition to the traditional patient care

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Major patients
* Proven pulmonary hypertension: PAPm ≥ 25mmHg, known PH
* Group 1,3,4 or 5 of the pulmonary hypertension classification
* Clinical stability \> 1 month clinically determined by clinician
* NYHA II or III class
* Signature of informed consent form following appropriate information
* Patient affiliated to the Social Security System

Exclusion Criteria

* Associated left heart disease
* Complex congenital heart disease
* Acoustic window which does not allow the echocardiography to be performed correctly
* Permanent cardiac arrhythmia
* NYHA IV class and NYHA I class
* Inability to perform at least a minimal effort on an ergometer
* Unstabilized acute coronary syndrome
* Compensatory heart failure
* Disturbances of ventricular rhythm veins, may not be narrowed.
* Prevalence of high-risk embolic intracardiac thrombus
* Prevalence of high-risk embolic intracardiac thrombus
* Preference of a medium to high abundance peericard-like thinning.
* Venous thromboembolic venous thromboembolic disease (\> 3 months)
* Left ventricular ejector obstruction (severe and/or symptomatic)
* Persons under guardianship, under curatorship, protected by law
* Persons deprived of their liberty
* Pregnant and parturient women
* Major not able or unable to express consent
* Minors
* Inability to perform cardiac rehabilitation
* Modynamic instability
* Follow-up impossible for geographical or psychological reasons
* Inadequate command of the French language
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire de Nice

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Pamela MOCERI, PH

Role: PRINCIPAL_INVESTIGATOR

Centre Hospitalier Universitaire de Nice

Locations

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Hôpital Pasteur

Nice, , France

Site Status

Countries

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France

Other Identifiers

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17-PP-09

Identifier Type: -

Identifier Source: org_study_id

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