Imaging Response to Immunotherapy and Radiation Therapy in Patients With Liver Metastases

NCT ID: NCT03401814

Last Updated: 2021-07-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-08-02

Study Completion Date

2019-12-12

Brief Summary

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Patients will be imaged with MRE at the time of the RT planning MRI, prior to the induction of RT and immunotherapy. Research imaging will be in addition to standard imaging studies performed at time points consistent with the standard of care (at the time of the RT planning MRI and the first clinical follow-up). An additional MRE exam will be performed at the end of treatment outside the standard of care imaging.

Detailed Description

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Conditions

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Liver Metastases

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Magnetic Resonance Elastography

rapidly developing technology for quantitatively assessing the mechanical properties of tissue, using externally applied mechanical waves

Intervention Type OTHER

Other Intervention Names

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MRE

Eligibility Criteria

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Inclusion Criteria

* Age ≥ 18 years
* Diagnosis of solid cancers with the presence of one or more liver metastases
* Minimum metastasis diameter ≥ 2 cm
* Planning to receive radiation therapy with immunotherapy
* Willingness to participate in mandatory imaging studies at Mayo Clinic Rochester

Exclusion Criteria

* Contraindications for MRI including claustrophobia, pace maker, metal implants, aneurism clips
* Patients who are not able to consent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mayo Clinic

OTHER

Sponsor Role lead

Responsible Party

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Sean S. Park

Radiation Oncology Consultant

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Sean Park, MD

Role: PRINCIPAL_INVESTIGATOR

Mayo Clinic

Locations

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Mayo Clinic

Rochester, Minnesota, United States

Site Status

Countries

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United States

Related Links

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Other Identifiers

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ROR1721

Identifier Type: OTHER

Identifier Source: secondary_id

17-009021

Identifier Type: -

Identifier Source: org_study_id

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