Preoxygenation Using High Flow Oxygen : Efficacy and Tolerance in Healthy Volunteers
NCT ID: NCT03399695
Last Updated: 2018-01-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
50 participants
INTERVENTIONAL
2018-01-02
2018-06-30
Brief Summary
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The goal of the present study is to measure end tidal oxygen after 3 min of preoxygenation using the recommended method (spontaneous breathing of 100% inhaled oxygen through a face mask) and using high flow nasal canula oxygen, in healthy volunteers.
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Detailed Description
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At the present time its use for preoxygenation before the induction of general anaesthesia in operating room has never been evaluated in term of end tidal oxygen fraction which is the gold standard measurement ensuring that the functional residual capacity has been filled with oxygen.
We planned a randomised cross over study in healthy volunteers studying efficacy and tolerance of preoxygenation using spontaneous ventilation with 100% inhaled oxygen through a face mask connected to the anaesthesia machine and preoxygenation using high flow nasal cannula oxygen (60l/min).
Conditions
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Study Design
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RANDOMIZED
CROSSOVER
TREATMENT
NONE
Study Groups
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control
spontaneous breathing through a face mask connected to the anaesthesia machine delivering 100% oxygen gas flow (15l/min)
preoxygenation
spontaneous breathing
ohd
spontaneous breathing through a nasal cannula connected to an humidifier device delivering warm (37°C) high flow oxygen(60l/min)
preoxygenation
spontaneous breathing
Interventions
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preoxygenation
spontaneous breathing
Eligibility Criteria
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Inclusion Criteria
* signed contentment
Exclusion Criteria
* pregnancy
18 Years
ALL
Yes
Sponsors
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University Hospital, Caen
OTHER
Responsible Party
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Locations
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University Hospital of Caen
Caen, , France
Countries
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Facility Contacts
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References
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Hanouz JL, Lhermitte D, Gerard JL, Fischer MO. Comparison of pre-oxygenation using spontaneous breathing through face mask and high-flow nasal oxygen: A randomised controlled crossover study in healthy volunteers. Eur J Anaesthesiol. 2019 May;36(5):335-341. doi: 10.1097/EJA.0000000000000954.
Other Identifiers
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ID RCB 2017-A02343-50
Identifier Type: -
Identifier Source: org_study_id
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