The Relationship Between Salt Restriction and Taste Sensitivity in Patients With Chronic Kidney Disease

NCT ID: NCT03397550

Last Updated: 2022-10-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Study Classification

OBSERVATIONAL

Study Start Date

2022-06-18

Study Completion Date

2023-05-01

Brief Summary

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The compliance of salt restriction in patients with CKD may be associated with taste sensitivity.

Detailed Description

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Conditions

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Renal Insufficiency, Chronic Chronic Kidney Diseases

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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salt restriction education

Salt intake target:\<5g/d Method:the standard salt restriction education will be lasting for 10-15 minutes by oral explanation at baseline.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* stage 3-5 CKD patients
* clinical stable

Exclusion Criteria

* renal replacement therapy
* cancer
* systemic infection
* Alzheimer's disease
* acute cardiovascular events, active hepatitis
* all other study-obstructive conditions
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Peking University First Hospital

OTHER

Sponsor Role lead

Responsible Party

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Dong Jie

Nephrology chief physician

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jie Dong

Role: STUDY_DIRECTOR

Peking Universiy First Hospital

Locations

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Peking University First Hospital

Beijing, , China

Site Status

Countries

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China

References

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Lynch KE, Lynch R, Curhan GC, Brunelli SM. Altered taste perception and nutritional status among hemodialysis patients. J Ren Nutr. 2013 Jul;23(4):288-295.e1. doi: 10.1053/j.jrn.2012.08.009. Epub 2012 Oct 6.

Reference Type RESULT
PMID: 23046735 (View on PubMed)

Kusaba T, Mori Y, Masami O, Hiroko N, Adachi T, Sugishita C, Sonomura K, Kimura T, Kishimoto N, Nakagawa H, Okigaki M, Hatta T, Matsubara H. Sodium restriction improves the gustatory threshold for salty taste in patients with chronic kidney disease. Kidney Int. 2009 Sep;76(6):638-43. doi: 10.1038/ki.2009.214. Epub 2009 Jun 10.

Reference Type RESULT
PMID: 19516246 (View on PubMed)

Middleton RA, Allman-Farinelli MA. Taste sensitivity is altered in patients with chronic renal failure receiving continuous ambulatory peritoneal dialysis. J Nutr. 1999 Jan;129(1):122-5. doi: 10.1093/jn/129.1.122.

Reference Type RESULT
PMID: 9915887 (View on PubMed)

McMahon EJ, Campbell KL, Bauer JD. Taste perception in kidney disease and relationship to dietary sodium intake. Appetite. 2014 Dec;83:236-241. doi: 10.1016/j.appet.2014.08.036. Epub 2014 Sep 2.

Reference Type RESULT
PMID: 25192896 (View on PubMed)

Other Identifiers

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pekingUFH-cn

Identifier Type: -

Identifier Source: org_study_id

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