The Utility of Platelet Rich Plasma in Hair Loss

NCT ID: NCT03376581

Last Updated: 2024-02-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

EARLY_PHASE1

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-11-28

Study Completion Date

2019-02-20

Brief Summary

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Platelet rich plasma (PRP) is an autologous preparation of human plasma with high concentration of platelets. Platelets release numerous growth factors, which stimulate cell proliferation and differentiation.

The purpose of this research is to investigate the potential of PRP injection for treatment of hair loss. Clinical outcomes will be assessed by noninvasive techniques including dermoscopy, multiphoton microscopy, optical coherence tomography, optical Doppler tomography and multispectral imaging.

Detailed Description

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Conditions

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Androgenetic Alopecia

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Prospective treatment

Group Type EXPERIMENTAL

Platelet rich plasma

Intervention Type PROCEDURE

Blood drawn from each participant will be spun down to separate platelets. Platelets will be injected into that patient's scalp.

Interventions

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Platelet rich plasma

Blood drawn from each participant will be spun down to separate platelets. Platelets will be injected into that patient's scalp.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Over 18 years of age
* Ability to understand and carry out instructions
* Diagnosed with alopecia

Exclusion Criteria

* Inability to understand and.or carry out instructions
* Pregnant women
* Use of any topical medication (such as minoxidil or any other solution for hair growth), oral medication (finasteride, dutasteride, or antiandrogens), laser therapy, or chemotherapy, within the preceding 4 weeks.
* Personal medical history of bleeding disorders
* Personal medical history of platelet dysfunction syndrome
* Anti-coagulation therapy or nonsteroidal anti-inflammatory drugs in the last 1 week.
Minimum Eligible Age

18 Years

Maximum Eligible Age

95 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of California, Irvine

OTHER

Sponsor Role lead

Responsible Party

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Natasha Mesinkovska

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University of California, Irvine, Department of Dermatology, Dermatology Clinical Research Center, Hewitt Hall

Irvine, California, United States

Site Status

Countries

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United States

Other Identifiers

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20163239

Identifier Type: -

Identifier Source: org_study_id

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