Exploring Nitrous Oxide Effects for Post Traumatic Stress Disorder (PTSD)

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

3 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-04-01

Study Completion Date

2020-04-05

Brief Summary

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The purpose of this study is to understand nitrous oxide effects in post traumatic stress disorder (PTSD)

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Detailed Description

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Post traumatic stress disorder (PTSD) is a disabling mental health disorder that impacts the lives of individuals. This study aims to understand nitrous oxide's effects in PTSD.

Conditions

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Post Traumatic Stress Disorder

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Nitrous Oxide

PTSD patients in this arm will receive a single inhalation dose of 50% nitrous oxide and 50% oxygen for 1 hour

Group Type EXPERIMENTAL

Nitrous Oxide

Intervention Type DRUG

One hour inhalation of 50% nitrous oxide, an odorless, colorless gas FDA approved as an induction agent for dental sedation

Interventions

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Nitrous Oxide

One hour inhalation of 50% nitrous oxide, an odorless, colorless gas FDA approved as an induction agent for dental sedation

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* age 18-80
* Veterans of the United States Uniformed Services
* primary diagnosis of PTSD
* sufficient severity of PTSD symptoms
* fluency in English
* capacity to provide informed consent