Bougiecap for Treatment of Benign Stenosis in GI Tract

NCT ID: NCT03349021

Last Updated: 2018-10-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-02-01

Study Completion Date

2018-09-01

Brief Summary

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Feasibility testing of a cap-assisted endoscopic bougienage for benign upper GI stenosis with direct optical control.

Detailed Description

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Benign stenosis in the GI tract are endoscopically treated by using Savary-Gilliard Dilators. This method, although sufficient in its interventional success, provides only haptic control and often requires wire guidance or X-ray imaging for monitoring the position of the stenosis, the dilator and the dilation process.

To guarantee the missing optical feedback and enhance the intraprocedural control a conical, clear cap was developed. This single use device is attachable to the front end of an endoscope and provides direct visual evaluation of the mucosal damage and progress of the Bougienage, making x-ray imaging obsolete while resulting in an effective dilation. For the bougienage treatment, the endoscope with the cap on top is inserted into the patient's GI tract and aimed at the stenosis. By pushing the endoscope forward the cone shaped cap expands the mucosal diameter by conversion of longitudinal to radial force vectors. Lateral and frontal openings allow suction and flush during procedure.

The clear tapering cap is now to be tested for ist technical feasibility and ability to improve patients' quality of life following treatment. Therefore a quality of life questionnaire (Swal QoL) evaluating the patients' dysphagia is done right before and two weeks after the bougienage and an effective dilation is proved by being able to pass the stenosis with the endoscope after the treatment.

Conditions

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Esophagostenosis

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Single Group interventional study
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Bougiecap

Treatment with Bougiecap instead of Savary Bougie

Group Type EXPERIMENTAL

Bougiecap

Intervention Type DEVICE

Treatment of esophagel Stenosis by Bougiecap

Interventions

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Bougiecap

Treatment of esophagel Stenosis by Bougiecap

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* benign Stenosis of the esophagus
* indication for endoscopic treamtent of stenosis

Exclusion Criteria

* no informed consent
* malignancy based Stenosis
* no indication for endoscopic treamtent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Ulm

OTHER

Sponsor Role lead

Responsible Party

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Alexander Meining

Head of Endoscopy

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Alexander Meining, Prof.

Role: PRINCIPAL_INVESTIGATOR

Head of Endoscopy

Locations

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Universitätklinikum Ulm

Ulm, Baden-Wurttemberg, Germany

Site Status

Marienhospital

Essen, , Germany

Site Status

Southhamptan University Hospital

Southhampton, , United Kingdom

Site Status

Countries

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Germany United Kingdom

References

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Walter B, Schmidbaur S, Rahman I, Albers D, Schumacher B, Meining A. The BougieCap - a new method for endoscopic treatment of complex benign esophageal stenosis: results from a multicenter study. Endoscopy. 2019 Sep;51(9):866-870. doi: 10.1055/a-0959-1535. Epub 2019 Jul 23.

Reference Type DERIVED
PMID: 31342473 (View on PubMed)

Other Identifiers

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1

Identifier Type: -

Identifier Source: org_study_id

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