Evaluation of Polyflex Stenting in Esophageal Cancer Patients

NCT ID: NCT00727376

Last Updated: 2020-08-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

26 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-03-31

Study Completion Date

2011-02-28

Brief Summary

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To evaluate the effectiveness of an esophageal stent as a way to maintain nutrition during radiation and/or chemotherapy treatment.

Detailed Description

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Conditions

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Esophageal Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Observation

Esophageal cancer patients

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* 18 years of age and older
* Willing and able to provide informed consent
* Willing to comply with follow-up requirements
* Biopsy-confirmed esophageal cancer (adenocarcinoma or squamous cell carcinoma) in mid or distal esophagus (clinical stage 3 or less)
* Indicated for chemotherapy and/or radiation therapy
* Ability to dilate stricture to 15mm diameter at extent of disease evaluation
* Placement of at least 18 x 23mm diameter and 120mm length PolyFlex stent

Exclusion Criteria

* Patients contraindicated for endoscopy
* Patients with prior esophageal stent placements
* Advance stage of disease, greater than T3 tumor or M1 disease
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Louisville

OTHER

Sponsor Role lead

Responsible Party

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Robert C. Martin

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Robert Martin, MD

Role: PRINCIPAL_INVESTIGATOR

University of Louisville

Locations

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University of Louisville

Louisville, Kentucky, United States

Site Status

Countries

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United States

References

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Martin RC 2nd, Cannon RM, Brown RE, Ellis SF, Williams S, Scoggins CR, Abbas AE. Evaluation of quality of life following placement of self-expanding plastic stents as a bridge to surgery in patients receiving neoadjuvant therapy for esophageal cancer. Oncologist. 2014 Mar;19(3):259-65. doi: 10.1634/theoncologist.2013-0344. Epub 2014 Feb 24.

Reference Type DERIVED
PMID: 24567281 (View on PubMed)

Brown RE, Abbas AE, Ellis S, Williams S, Scoggins CR, McMasters KM, Martin RC 2nd. A prospective phase II evaluation of esophageal stenting for neoadjuvant therapy for esophageal cancer: optimal performance and surgical safety. J Am Coll Surg. 2011 Apr;212(4):582-8; discussion 588-9. doi: 10.1016/j.jamcollsurg.2010.12.026.

Reference Type DERIVED
PMID: 21463793 (View on PubMed)

Other Identifiers

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08-0132

Identifier Type: -

Identifier Source: org_study_id

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