Pre-operative Blood Lipid Level and Post-operative Major Adverse Cardiac Event

NCT ID: NCT03344224

Last Updated: 2018-01-04

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 50000 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2017-01-01
• Study Completion Date: 2017-09-20

Brief Summary

Whether the pre-operative blood lipid level and post-operative cardiovascular events is associated is unknown. This study is to find out the main blood lipid and relative protein level change and the post-operative cardiovascular events occurrence.

Detailed Description

The participants collected data from their hospital.Patients under going non-cardiac surgery were collected. Data of Triglycerides, cholesterol, Low-density lipoprotein and High-density lipoprotein were collected perioperatively. The postoperative major cardiovascular and cerebral events were also identified and collected. Other data including perioperative information and surgeries and anesthesia data were gathered.

Logistic regression models were built and selected. Independent risk factors relative to postoperative major cardiovascular and cerebral events were screened and identified. different levels of Triglycerides, cholesterol, Low-density lipoprotein and High-density lipoprotein were analysed.

Conditions

Lipid Metabolism Disorders; Postoperative Complications

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: RETROSPECTIVE

Study Groups

normal blood lipid/protein group

laboratory test

Intervention Type: DIAGNOSTIC_TEST

laboratory test

abnormal blood lipid/protein group

laboratory test

Intervention Type: DIAGNOSTIC_TEST

laboratory test

Interventions

laboratory test

laboratory test

Intervention Type: DIAGNOSTIC_TEST

Eligibility Criteria

Inclusion Criteria

• non-cardiac surgery patients with preoperative blood lipid tests

Exclusion Criteria

• electronic records missing or peri-operative data missing

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 100 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Peking University First Hospital

OTHER

Sponsor Role: lead

Responsible Party

Yan Zhou, MD

Principal Investigator,

Responsibility Role: PRINCIPAL_INVESTIGATOR

References

Leardi S, Altilia F, Delmonaco S, Cianca G, Pietroletti R, Simi M. [Blood levels of cholesterol and postoperative septic complications]. Ann Ital Chir. 2000 Mar-Apr;71(2):233-7. Italian.

Reference Type: BACKGROUND

PMID: 10920496 (View on PubMed)

Other Identifiers

LMACE

Identifier Type: -

Identifier Source: org_study_id