Epidemiology of Resistant Microbial Strains Among Different Groups of People (Healthy, Infected and Exposed to Animals)

NCT ID: NCT03343119

Last Updated: 2018-10-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

708 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-03-27

Study Completion Date

2019-08-31

Brief Summary

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This study investigates carriage rate and risk factors for acquiring multiresistant bacteria (ESBL producing E.coli and K.pneumoniae, carbapenem-resistant and multidrug resistant P.aeruginosa, MRSA and VRE) in hospitalised patients and healthy volunteers.

Detailed Description

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Conditions

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ESBL Producing E.Coli ESBL Producing K.Pneumoniae Multidrug Resistant P.Aeruginosa Carbapenem Resistant P.Aeruginosa Methicillin Resistant Staphylococcus Aureus (MRSA) Vancomycin (Glycopeptide) Resistant Enterococcus (VRE)

Study Design

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Observational Model Type

ECOLOGIC_OR_COMMUNITY

Study Time Perspective

OTHER

Study Groups

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Hospitalised patients

No intervention

No interventions assigned to this group

Healthy volunteers

No intervention

No interventions assigned to this group

Dog owners (healthy volunteers)

No intervention

No interventions assigned to this group

Veterinarians (healthy volunteers)

No intervention

No interventions assigned to this group

Pig farmers (healthy volunteers)

No intervention

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* MDR bacteria (listed above) isolated from clinical specimen
* hospitalisation to the Tartu University Hospital or North Estonia Medical Centre or West Tallinn Central Hospital or East-Tallinn Central Hospital or The Hospital of Reconstructive Surgery


* age \>6 months
* have not received any antibacterial treatment in previous 3 months
* have not been hospitalised in previous 3 months


* age \>6 months
* have not received any antibacterial treatment in previous 3 months
* have not been hospitalised in previous 3 months
* owning a dog


* have not received any antibacterial treatment in previous 3 months
* have not been hospitaliZed in previous 3 months
* working as a veterinarian


* have not received any antibacterial treatment in previous 3 months
* have not been hospitalized in previous 3 months
* occupation as a pig farmer
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Estonian University of Life Sciences

OTHER

Sponsor Role collaborator

University of Tartu

OTHER

Sponsor Role lead

Responsible Party

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Kaidi Telling

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Tanel Tenson, PhD

Role: STUDY_DIRECTOR

University of Tartu

References

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Telling K, Laht M, Brauer A, Remm M, Kisand V, Maimets M, Tenson T, Lutsar I. Multidrug resistant Pseudomonas aeruginosa in Estonian hospitals. BMC Infect Dis. 2018 Oct 11;18(1):513. doi: 10.1186/s12879-018-3421-1.

Reference Type DERIVED
PMID: 30309321 (View on PubMed)

Other Identifiers

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SLOTI12038T

Identifier Type: -

Identifier Source: org_study_id

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