Continuous Monitoring and Control of Hypoglycemia

NCT ID: NCT03340831

Last Updated: 2021-09-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

1388 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-10-20

Study Completion Date

2023-12-30

Brief Summary

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Evaluate safety of non-adjunctive CGM use in CGM naive participants.

Detailed Description

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The study comprises recruitment and consenting of pediatric and adult participants. At entry, the following information will be collected: demographics, labs, clinical and diabetes history information (history of mild/severe hypoglycemia or DKA events in the past 6 months and SMBG testing frequency). There are 3 clinic visits: Study Entry, Month 6 and Month 12 . Monthly phone contacts will be made to assess for any mild/severe hypoglycemic or DKA events and any details surrounding an event. Clinic visits at Months 6 and 12 will capture frequency of SMBG testing, A1C level and PRO information. CGM data will be obtained during the study to assess for CGM adherence.

Conditions

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Diabetes

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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CGM/BGM Group

single-group, whereby participant is their own control. Use of a Blood Glucose Meter (BGM) for 6 months is compared to use of the G5 and G6 CGM System for 6 months, with collection of major diabetes related events (mild/severe hypoglycemia and DKA).

Continuous Glucose Monitoring (CGM)

Intervention Type DEVICE

Use of CGM to compare incidence of diabetes events compared to use of a blood glucose meter (BGM)

Interventions

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Continuous Glucose Monitoring (CGM)

Use of CGM to compare incidence of diabetes events compared to use of a blood glucose meter (BGM)

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Naïve to real-time CGM
* Type 1 or insulin-requiring Type 2 diabetes
* ≥ 2 years old

Exclusion Criteria

* Use of RT-CGM, within the past 12 months
* Pregnancy
* Concomitant disease or condition that may compromise patient safety including and not limited to severe mental illness, a diagnosed or suspected eating disorder or any uncontrolled long term medical condition that would interfere with study related tasks or visits, or ongoing treatment for a significant malignancy.
* Known (or suspected) significant allergy to medical grade adhesives
* Dialysis
Minimum Eligible Age

2 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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DexCom, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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David Price, MD

Role: STUDY_DIRECTOR

Dexcom-Medical Affairs

Locations

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Scripps Whittier Diabetes Institute

La Jolla, California, United States

Site Status COMPLETED

Diabetes and Endocrine Associates

La Mesa, California, United States

Site Status COMPLETED

Centre of Excellence in Diabetes and Endocrinology

Sacramento, California, United States

Site Status RECRUITING

Mills-Peninsula Medical Center

San Mateo, California, United States

Site Status COMPLETED

Sansum Diabetes Research Institute

Santa Barbara, California, United States

Site Status COMPLETED

University of Florida Pediatric Endocrinology

Gainesville, Florida, United States

Site Status ACTIVE_NOT_RECRUITING

Intervent Clinical Research Center

Pembroke Pines, Florida, United States

Site Status RECRUITING

University of South Florida Clinical Research Center

Tampa, Florida, United States

Site Status RECRUITING

Atlanta Diabetes

Atlanta, Georgia, United States

Site Status COMPLETED

Rocky Mountain Diabetes Center

Idaho Falls, Idaho, United States

Site Status COMPLETED

Northshore University Health System

Skokie, Illinois, United States

Site Status COMPLETED

Iowa Diabetes & Endocrinology Research Center

Des Moines, Iowa, United States

Site Status COMPLETED

Cotton O'Neil Clinical Research

Topeka, Kansas, United States

Site Status RECRUITING

International Diabetes Research Center

Minneapolis, Minnesota, United States

Site Status COMPLETED

Children's Mercy Hospital

Kansas City, Missouri, United States

Site Status RECRUITING

Methodist Physicians Clinic - Diabetes and Endocrine Specialists

Omaha, Nebraska, United States

Site Status COMPLETED

Mountain Diabetes and Endocrine Center

Asheville, North Carolina, United States

Site Status COMPLETED

Carteret Medical Group

Morehead City, North Carolina, United States

Site Status COMPLETED

Diabetes & Endocrinology Consultants, PC

Morehead City, North Carolina, United States

Site Status COMPLETED

University of Oklahoma Health Sciences Center Department of Pediatric Diabetes and Endocrinology

Oklahoma City, Oklahoma, United States

Site Status RECRUITING

Vanderbilt Eskind Diabetes Clinic

Nashville, Tennessee, United States

Site Status COMPLETED

Amarillo Medical Specialists, LLP

Amarillo, Texas, United States

Site Status RECRUITING

Texas Diabetes and Endocrine

Austin, Texas, United States

Site Status COMPLETED

Research Institute of Dallas

Dallas, Texas, United States

Site Status COMPLETED

Advanced Research Associates

Ogden, Utah, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Stayce Beck, PhD, MPH

Role: CONTACT

8582036454

Nelly Njeru

Role: CONTACT

8582036379

Facility Contacts

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Mila Melnik

Role: primary

Marisela Rodriguez

Role: primary

954-507-6627

Ponja Hemphill

Role: primary

Janet Rodriguez

Role: backup

Jaime Berroth

Role: primary

Jennifer L James

Role: primary

LInda Weber

Role: primary

Becky Cota, RN, CDE

Role: primary

806-358-8331

Hilary Wahlen

Role: primary

801-409-2040

Other Identifiers

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PTL-901895

Identifier Type: -

Identifier Source: org_study_id

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