Clinical Significance of Detecting CEA and CK20 mRNA-positive Cells in Colorectal Cancer Patients

NCT ID: NCT03337347

Last Updated: 2019-10-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

256 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-01-01

Study Completion Date

2015-10-23

Brief Summary

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To determine whether the presence of circulating/disseminated tumor cells (CTCs/DTCs) in the blood and bone marrow of colorectal cancer (CRC) patients with localized disease is a negative prognostic factor, and to find correlations with other clinical/pathological disease characteristics.

Detailed Description

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Conditions

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Colorectal Cancer Circulating Tumor Cell

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Interventions

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CTC/DTC count

The presence of CTCs/DTCs in the peripheral blood and/or bone marrow may identify colorectal cancer patients with high risk of disease recurrence who may benefit from adjuvant therapy.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

\- colorectal adenocarcinoma

Exclusion Criteria

* prior neoadjuvant chemoradiotherapy
* prior colorectal cancer
* cancer duplicity
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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The Institute of Molecular and Translational Medicine, Czech Republic

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Miloslav Duda, MD

Role: PRINCIPAL_INVESTIGATOR

University Hospital Olomouc

Locations

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University Hospital Olomouc

Olomouc, , Czechia

Site Status

Countries

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Czechia

Other Identifiers

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CTC_CRC_2017

Identifier Type: -

Identifier Source: org_study_id

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