Trial Outcomes & Findings for Investigating Accelerated Learning and Memory in Healthy Subjects Using a Face Name Memory Task (NCT NCT03309072)

Last Updated: 2022-02-03

Results Overview

All participants performed a face memory task .The face stimuli consisted of 120 grayscale pictures of human faces. Only faces with a neutral expression facing forward were selected. Half of the faces were male, and the other half were female. The face-name association memory task was divided into (1) an encoding phase, (2) a consolidation phase, and (3) a retrieval phase. During the encoding phase, participants studied 60 successively presented face-name pairs and were instructed to assess their gender to keep them focused to the task. The encoding phase was followed by a consolidation phase where participants were instructed to "sit still, relax, and think about nothing in particular" for 10 minutes, During the retrieval phase, participants were presented with 60 old and 60 new faces and were instructed to assess whether they have seen this face during the encoding phase. The outcome was the percent of Correct Name to Face Matches

Recruitment status

COMPLETED

Study phase

Target enrollment

30 participants

Primary outcome timeframe

Associate Memory is assessed after a 10 minutes break following the study phase

Results posted on

2022-02-03

Participant Flow

1. Age between 18 and 35 2. Currently not using any medication 3. Native English speaker 4. Capable of understanding and signing an informed consent

Participant milestones

Participant milestones
Measure	Active tDCS active tDCS with Face Name associate Memory task tDCS: active tDCS	Sham tDCS sham tDCS with Face Name associate Memory task sham tDCS: sham tDCS
Overall Study STARTED	15	15
Overall Study COMPLETED	15	15
Overall Study NOT COMPLETED	0	0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Investigating Accelerated Learning and Memory in Healthy Subjects Using a Face Name Memory Task

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	Active tDCS n=15 Participants active tDCS with Face Name associate Memory task tDCS: active tDCS	Sham tDCS n=15 Participants sham tDCS with Face Name associate Memory task sham tDCS: sham tDCS	Total n=30 Participants Total of all reporting groups
Age, Continuous	19.67 years STANDARD_DEVIATION 2.5 • n=5 Participants	20.6 years STANDARD_DEVIATION 3.9 • n=7 Participants	20.13 years STANDARD_DEVIATION 3.26 • n=5 Participants
Sex: Female, Male Female	10 Participants n=5 Participants	12 Participants n=7 Participants	22 Participants n=5 Participants
Sex: Female, Male Male	5 Participants n=5 Participants	3 Participants n=7 Participants	8 Participants n=5 Participants
Race (NIH/OMB) American Indian or Alaska Native	0 Participants n=5 Participants	0 Participants n=7 Participants	0 Participants n=5 Participants
Race (NIH/OMB) Asian	5 Participants n=5 Participants	8 Participants n=7 Participants	13 Participants n=5 Participants
Race (NIH/OMB) Native Hawaiian or Other Pacific Islander	0 Participants n=5 Participants	0 Participants n=7 Participants	0 Participants n=5 Participants
Race (NIH/OMB) Black or African American	0 Participants n=5 Participants	1 Participants n=7 Participants	1 Participants n=5 Participants
Race (NIH/OMB) White	6 Participants n=5 Participants	4 Participants n=7 Participants	10 Participants n=5 Participants
Race (NIH/OMB) More than one race	1 Participants n=5 Participants	2 Participants n=7 Participants	3 Participants n=5 Participants
Race (NIH/OMB) Unknown or Not Reported	3 Participants n=5 Participants	0 Participants n=7 Participants	3 Participants n=5 Participants
Region of Enrollment United States	15 participants n=5 Participants	15 participants n=7 Participants	30 participants n=5 Participants
Beck Depression Inventory Scale	5.20 units on a scale STANDARD_DEVIATION 3.61 • n=5 Participants	3.47 units on a scale STANDARD_DEVIATION 3.62 • n=7 Participants	4.33 units on a scale STANDARD_DEVIATION 3.66 • n=5 Participants
Beck Anxiety Inventory Scale	4.53 units on a scale STANDARD_DEVIATION 3.38 • n=5 Participants	2.67 units on a scale STANDARD_DEVIATION 2.85 • n=7 Participants	3.60 units on a scale STANDARD_DEVIATION 3.21 • n=5 Participants
Mini Mental State Examination	28.9 units on a scale STANDARD_DEVIATION 0.88 • n=5 Participants	28.5 units on a scale STANDARD_DEVIATION 1.51 • n=7 Participants	28.7 units on a scale STANDARD_DEVIATION 1.24 • n=5 Participants
Profile of Mood States- Mood Disturbance	10.27 units on a scale STANDARD_DEVIATION 23.2 • n=5 Participants	1.47 units on a scale STANDARD_DEVIATION 11.33 • n=7 Participants	4.4 units on a scale STANDARD_DEVIATION 18.9 • n=5 Participants

PRIMARY outcome

Timeframe: Associate Memory is assessed after a 10 minutes break following the study phase

Outcome measures

Outcome measures
Measure	Active tDCS n=15 Participants active tDCS with Face Name associate Memory task tDCS: active tDCS	Sham tDCS n=15 Participants sham tDCS with Face Name associate Memory task sham tDCS: sham tDCS
Associative Memory Assessed by a Face Name Associate Memory Experiment	44.22 Percent of Correct Name to Face Matches Standard Deviation 11.54	35.44 Percent of Correct Name to Face Matches Standard Deviation 12.04

Adverse Events

Active tDCS

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Sham tDCS

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Sven Vanneste, Principal Investigator

University of Texas at Dallas

Phone: 972-883-7277

Email: [email protected]

Results disclosure agreements

Principal investigator is a sponsor employee
Publication restrictions are in place