Yoga for Symptoms of Nerve Damage Caused by Chemotherapy

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

51 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-09-18

Study Completion Date

2020-09-15

Brief Summary

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Some types of chemotherapy used to treat breast cancer can cause damage to nerves with symptoms like tingling, numbness, muscle weakness, and pain in the hands and feet that can last and can affect functioning. The purpose of this study is to find out the effects of yoga on reducing symptoms caused by such nerve damage.

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Detailed Description

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Conditions

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Breast Cancer Peripheral Neuropathy Gynecologic Cancer

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Yoga Arm

After randomization, participants in the Yoga group will meet twice weekly for 8 weeks of classes taught by MSK yoga instructors. Each class will last for sixty minutes. In addition to these group classes, participants will utilize a home-based program on the days group classes are not held. The daily home practice will continue for four weeks after the group classes are finished.

Group Type EXPERIMENTAL

Yoga

Intervention Type OTHER

Participants in the Yoga group will meet twice weekly for 8 weeks of classes taught by MSK yoga instructors. Each class will last for sixty minutes. In addition to these group classes, participants will utilize a home-based program on the days group classes are not held. The daily home practice will continue for four weeks after the group classes are finished.

Wait List Control Arm (WLC)

Participants in the WLC group will continue usual care for twelve weeks before participating in Yoga classes for eight weeks. At the end of the twelve week follow-up, these participants will receive eight weeks of group Yoga classes and the home Yoga practice recording. At week 20, they will complete a final follow-up visit.

Group Type ACTIVE_COMPARATOR

Wait List Control

Intervention Type OTHER

Participants in the WLC group will continue usual care for twelve weeks before participating in Yoga classes for eight weeks. At the end of the twelve week follow-up, these subjects will receive eight weeks of group Yoga classes and the home Yoga practice recording. At week 20, they will complete a final follow-up visit.

Interventions

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Yoga

Participants in the Yoga group will meet twice weekly for 8 weeks of classes taught by MSK yoga instructors. Each class will last for sixty minutes. In addition to these group classes, participants will utilize a home-based program on the days group classes are not held. The daily home practice will continue for four weeks after the group classes are finished.

Intervention Type OTHER

Wait List Control

Participants in the WLC group will continue usual care for twelve weeks before participating in Yoga classes for eight weeks. At the end of the twelve week follow-up, these subjects will receive eight weeks of group Yoga classes and the home Yoga practice recording. At week 20, they will complete a final follow-up visit.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* English-speaking
* Age \>/= 18 years old
* Survivors with a primary diagnosis of stage I-III breast, ovarian uterine, or endometrial cancer
* Moderate to severe chemotherapy induced peripheral neuropathy, defined by symptoms such as numbness, tingling, or pain ratings of 4 or greater on a 0-10 numeric rating scale
* Have completed neurotoxic chemotherapy, i.e. taxanes (paclitaxel, docetaxel) and platinum (carboplatin) at least 3 months prior to enrollment
* If taking anti-neuropathy medications, they are on a stable regiment (no change in 3 months)
* ECOG performance status 0-2

* English speaking
* Age \>/= 18 years old
* Survivors with a primary diagnosis of Stage I-III breast, ovarian, uterine, or endometrial cancer
* CIPN symptoms such as numbness, tingling, or pain ratings \< 2 on a 0-10 NRS scale
* Have completed neurotoxic chemotherapy, i.e. taxanes (paclitaxel, docetaxel) and platinum (carboplatin) at least 3 months prior to enrollment
* ECOG performance status 0-2

Exclusion Criteria

* Participants with metastatic disease
* Participants who are currently receiving physical therapy or practicing yoga for any reason

* Patients with metastatic disease
* Patients taking anti-neuropathy medication
* Patients who are currently receiving physical therapy or practicing yoga for any reason

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No