Serum Progesterone on the Day of Embryo Transfer and Pregnancy Rate.
NCT ID: NCT03272412
Last Updated: 2019-01-31
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
1205 participants
OBSERVATIONAL
2017-09-08
2018-11-28
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Interventions
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Analysis of serum Progesterone in blood sample
Levels of progesterone will be determined on the day of embryo transfer in patients undergoing artificial endometrial preparation cycles.
Eligibility Criteria
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Inclusion Criteria
2. Hormonal Replacement therapy cycle for embryo transfer in any of the following situations:
1. Embryos in fresh cycle with donated oocytes.
2. Subsequent embryo transfers of vitrified embryos in cycles of donated oocytes.
3. Frozen embryo transfers in cycles with autologous oocytes.
3. Endometrial line: \>6.5-7mm (with trilaminar aspect) in proliferative phase, before introducing progesterone.
4. Administration of natural micronized progesterone intravaginally (400 mg/12 hours for 5 complete days (10 dosis), before the embryo transfer and maintained until pregnancy week 12.
5. Embryo transfer of blastocyst (day 5-6).
6. Signed Informed Consent
Exclusion Criteria
2. Simultaneous participation in another clinical study.
3. Participation in another clinical study before the inclusion in the present study, and which could affect the objectives of the present study.
18 Years
50 Years
FEMALE
No
Sponsors
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Instituto Valenciano de Infertilidad, IVI VALENCIA
OTHER
Responsible Party
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Elena Labarta
Gynecologist IVI Valencia
Locations
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Instituto Valenciano de Infertilidad Spain
Valencia, , Spain
Countries
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References
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Labarta E, Mariani G, Paolelli S, Rodriguez-Varela C, Vidal C, Giles J, Bellver J, Cruz F, Marzal A, Celada P, Olmo I, Alama P, Remohi J, Bosch E. Impact of low serum progesterone levels on the day of embryo transfer on pregnancy outcome: a prospective cohort study in artificial cycles with vaginal progesterone. Hum Reprod. 2021 Feb 18;36(3):683-692. doi: 10.1093/humrep/deaa322.
Other Identifiers
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1704-VLC-024-EL
Identifier Type: -
Identifier Source: org_study_id
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