Predictive Factors and Complications of Delirium

NCT ID: NCT03246165

Last Updated: 2019-03-26

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 173 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2011-09-01
• Study Completion Date: 2015-06-30

Brief Summary

The objective of this research was to determine the incidence, predisposing and triggering factors of delirium following cardiac surgery and its consequences within 30 days of surgery and during a 12-18-month follow-up in older adult patients.

Detailed Description

Delirium is a transient and fluctuating course syndrome of acute onset that is characterized by reduced level of consciousness, global cognitive dysfunction, and disorder in the sleep-wake cycle. In patients undergoing cardiac surgery, delirium is a complication that affects 2-57% of the patients, reaching as high as 73% in older subjects.

The identification of patients at high risk for delirium is important to deliver proper care and avoid the consequences of this complication. However, previous studies published on the subject have not delivered definitive results in the cardiac surgery setting. Low educational level has also been studied as a risk factor for delirium after surgery but never in a group of cardiac surgery patients that includes a significant rate of illiteracy.

The objective of this research was to determine the incidence, predisposing and triggering factors of delirium following cardiac surgery and its consequences within 30 days of surgery and during a 12-18-month follow-up in older adult patients.

Conditions

Delirium; Surgery--Complications; Age Problem

Study Design

• Observational Model Type: CASE_CONTROL
• Study Time Perspective: PROSPECTIVE

Interventions

Cardiac surgery

Coronary bypass, heart valve replacement

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• Elective cardiovascular surgery

Exclusion Criteria

• Blindness,
• deafness,
• previous stroke
• dementia
• delirium at inclusion, preoperatively
• creatinine clearance < 30 ml/min
• emergency surgery

• Minimum Eligible Age: 60 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Hospital de Messejana

UNKNOWN

Sponsor Role: collaborator

University of Sao Paulo

OTHER

Sponsor Role: lead

Responsible Party

Bruno Caramelli

Associate Professor of Cardiology

Responsibility Role: PRINCIPAL_INVESTIGATOR

Other Identifiers

825/11

Identifier Type: -

Identifier Source: org_study_id