Effects of Phytonutrients Upon Muscle Perfusion in Response to Feeding

NCT ID: NCT03213340

Last Updated: 2020-01-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

39 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-09-14

Study Completion Date

2019-10-02

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This is a random order cross over design trial to evaluate the efficacy of select nutritional ingredients on enhancing muscle perfusion in response to an acute meal stimulus.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Biological Aging

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

3 cohorts, crossover within cohort
Primary Study Purpose

OTHER

Blinding Strategy

SINGLE

Participants

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Catechin Cohort 1

2 treatment - Experimental Catechin Blend; Control 1 Placebo

Group Type EXPERIMENTAL

Catechin Cohort 1

Intervention Type OTHER

\- 4 capsules taken with water 1 hour prior to meal

Curcuminoid Cohort 2

2 treatment - Experimental Curcuminoid Blend; Control 1 Placebo

Group Type EXPERIMENTAL

Curcuminoid Cohort 2

Intervention Type OTHER

\- 2 capsules taken with water 1 hour prior to meal

Flavonoid Cohort 3

2 treatment - Experimental Flavonoid Blend; Control 2 Low-Flavonoid Blend

Group Type EXPERIMENTAL

Flavonoid Cohort 3

Intervention Type OTHER

\- \~ 1 oz. serving consumed 30 minutes before meal

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Catechin Cohort 1

\- 4 capsules taken with water 1 hour prior to meal

Intervention Type OTHER

Curcuminoid Cohort 2

\- 2 capsules taken with water 1 hour prior to meal

Intervention Type OTHER

Flavonoid Cohort 3

\- \~ 1 oz. serving consumed 30 minutes before meal

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Body mass index (BMI) 18-30 kg/m2
* Free from active metabolic disease
* Normotensive

Exclusion Criteria

* Habitual gym use or formal exercise (more than once a week) or other routine strenuous physical activity
* Smokers
* Surgery within past 3 months
* Active cardiovascular disease
* Taking beta-adrenergic blocking agents
* Cerebrovascular disease:
* Active respiratory disease
* Active metabolic disease
* Active inflammatory bowel or renal disease
* Active Malignancy or until confirmed remission
* Clotting dysfunction
* History of DVT
* Significant musculoskeletal or neurological disorders
* Family history of early (\<55y) death from cardiovascular disease
* Known sensitivity to Sonovue contrast agent
* Known allergy or intolerance to any of the study ingredients
* Current use of any of the study ingredients
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Abbott Nutrition

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Suzette Pereira, PhD

Role: STUDY_CHAIR

Abbott Nutrition

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

University of Nottingham

Derby, , United Kingdom

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United Kingdom

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

BL31

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

NEUROmuscular Training for Enhanced AGE Longevity
NCT06620666 ACTIVE_NOT_RECRUITING NA
Aged Garlic Extract Study
NCT03860350 COMPLETED NA
COMP-4 Supplementation and Brachial Artery FMD
NCT05595915 ACTIVE_NOT_RECRUITING PHASE1/PHASE2