Comparison of Enhanced Recovery After Surgery (ERAS) Pathway With Conventional Pathway After Laparoscopic Sleeve Gastrectomy

NCT ID: NCT03191318

Last Updated: 2018-10-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-09-01

Study Completion Date

2018-08-01

Brief Summary

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The aim of this study is to compare two postoperative recovery pathways namely, enhanced recovery after surgery (ERAS) pathway and conventional recovery pathway after laparoscopic sleeve gastrectomy with respect to outcomes including hospital stay, postoperative pain and other postoperative outcomes.

Detailed Description

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The Enhanced recovery after surgery (ERAS) pathway, initially introduced for colorectal surgery, is an evidence based perioperative pathway which has resulted in earlier recovery, less pain, and lower complication rates. Bariatric surgical patients, without severe co-morbidities, are good candidates for ERAS pathway, but the application of ERAS concepts has been limited in this field, specially, in Asia.

Although the current literature shows that 2 randomized clinical trials (RCT) have been performed for application of ERAS in bariatric surgery, data is still scarce as per outcomes with respect to postoperative pain and analgesic usage. One of the RCTs has compared with historical controls and both the RCTs have not clearly defined their conventional standard pathways. In this study, the investigators have clearly defined both ERAS pathway and standard pathway leaving no ambiguity.

This study is a prospective, randomized, parallel group trial comparing ERAS pathway and standard pathway after laparoscopic sleeve gastrectomy in relation to the hospital stay, postoperative pain, complications and other perioperative parameters.

This is a single institute based trial, being conducted at GEM hospital and research centre, Coimbatore, TN, India. The trial has been approved by the GEM Hospital ethical committee.

In this trial, the investigators are planning to enroll participants with morbid obesity planned to undergo laparoscopic sleeve gastrectomy. After full assessment, informed consent, these participants will be randomised using computer generated random numbers either into ERAS pathway group or into Standard pathway group.

All the intraoperative and perioperative details with respect to anaesthetic drugs usage, intravenous fluid requirement, time to ambulation, time to oral liquids, postoperative pain score, analgesic requirement and hospital stay will be recorded in the proforma.

Conditions

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Morbid Obesity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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ERAS pathway

Laparoscopic sleeve gastrectomy with ERAS pathway

Group Type ACTIVE_COMPARATOR

ERAS pathway

Intervention Type OTHER

ERAS pathway after laparoscopic sleeve gastrectomy

Standard pathway

Laparoscopic sleeve gastrectomy with standard pathway

Group Type ACTIVE_COMPARATOR

Standard pathway

Intervention Type OTHER

Standard pathway after laparoscopic sleeve gastrectomy

Interventions

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ERAS pathway

ERAS pathway after laparoscopic sleeve gastrectomy

Intervention Type OTHER

Standard pathway

Standard pathway after laparoscopic sleeve gastrectomy

Intervention Type OTHER

Other Intervention Names

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Fast track pathway Coventional pathway

Eligibility Criteria

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Inclusion Criteria

* All patients undergoing laparoscopic sleeve gastrectomy during this study period

Exclusion Criteria

* 1\. Redo procedures 2. ASA III and above status 3. Previous major upper abdominal surgeries 4. Not willing to participate
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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GEM Hospital & Research Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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C Palanivelu, MS, MCh

Role: STUDY_CHAIR

GEM Hospital & Research centre

P Praveen Raj, MS, DNB

Role: STUDY_DIRECTOR

GEM Hospital and Research centre

M S Prabhakaran, DA

Role: PRINCIPAL_INVESTIGATOR

GEM Hospital & Research centre

Siddhartha Bhattacharya, MS, DNB, FNB

Role: PRINCIPAL_INVESTIGATOR

GEM Hospital & Research centre

Locations

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Gem Hospital and Research Centre

Coimbatore, Tamil Nadu, India

Site Status

Countries

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India

References

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Pimenta GP, Capellan DA, de Aguilar-Nascimento JE. Sleeve Gastrectomy With or Without a Multimodal Perioperative Care. A Randomized Pilot Study. Obes Surg. 2015 Sep;25(9):1639-46. doi: 10.1007/s11695-015-1573-2.

Reference Type BACKGROUND
PMID: 25670530 (View on PubMed)

Lemanu DP, Singh PP, Berridge K, Burr M, Birch C, Babor R, MacCormick AD, Arroll B, Hill AG. Randomized clinical trial of enhanced recovery versus standard care after laparoscopic sleeve gastrectomy. Br J Surg. 2013 Mar;100(4):482-9. doi: 10.1002/bjs.9026. Epub 2013 Jan 21.

Reference Type BACKGROUND
PMID: 23339040 (View on PubMed)

Prabhakaran S, Misra S, Magila M, Kumar SS, Kasthuri S, Palanivelu C, Raj PP. Randomized Controlled Trial Comparing the Outcomes of Enhanced Recovery After Surgery and Standard Recovery Pathways in Laparoscopic Sleeve Gastrectomy. Obes Surg. 2020 Sep;30(9):3273-3279. doi: 10.1007/s11695-020-04585-2.

Reference Type DERIVED
PMID: 32291702 (View on PubMed)

Other Identifiers

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BARI-01

Identifier Type: -

Identifier Source: org_study_id

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