Stellate Ganglion Block on Tourniquet Response

NCT ID: NCT03181672

Last Updated: 2017-06-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-06-02

Study Completion Date

2018-12-31

Brief Summary

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To investigate the influence of stellate ganglion block on tourniquet response during surgery in patients undergoing elective lower limb Department of orthopedics.

Detailed Description

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Select elective general anesthesia in 100 cases of lower extremity Department of orthopedics surgery patients were randomly divided into SGB group and control group, SGB group received anesthesia before the right stellate ganglion block intervention, the control group underwent right deltoid muscle injection, changes in hemodynamics in two groups were recorded in heart rate, blood pressure, and before anesthesia, after intubation 3min 1H, a tourniquet, tourniquet release before and after tourniquet release 3min, 30min, changes in blood physiological analysis. The effect of stellate ganglion block on tourniquet response during perioperative period was observed.

Conditions

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Stellate Ganglion Block

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Stellate ganglion block

Stellate ganglion block

Group Type ACTIVE_COMPARATOR

Stellate ganglion block

Intervention Type PROCEDURE

Stellate ganglion block with 1% lidocaine 10ml

control group

Deltoid muscle injection

Group Type PLACEBO_COMPARATOR

control group

Intervention Type PROCEDURE

Deltoid muscle injection with 1% lidocaine 10ml

Interventions

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Stellate ganglion block

Stellate ganglion block with 1% lidocaine 10ml

Intervention Type PROCEDURE

control group

Deltoid muscle injection with 1% lidocaine 10ml

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* American Society of anesthesiologists Grade 1-3 Patients
* undergoing lower limb surgery under general anesthesia
* should be treated with tourniquet

Exclusion Criteria

* Tourniquet application time is less than 1h, greater than 1.5h
* Abnormal coagulation function
* perioperative application of hormone
* lidocaine allergy
* can not cope with nerve block
* nerve block failure
* minimally invasive surgery
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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The Affiliated Hospital of Xuzhou Medical University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Tie Xu, MD

Role: STUDY_DIRECTOR

The Affiliated Hospital of Xuzhou Medical University

Locations

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The Affiliated Hospital of Xuzhou Medical University

Xuzhou, Jiangsu, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Tie Xu, MD

Role: CONTACT

13952110889

Shuangshuang Meng, bachelor

Role: CONTACT

15862167035

Facility Contacts

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Shuangshuang Meng, bachelor

Role: primary

15862167035

References

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Arai YC, Ogata J, Matsumoto Y, Yonemura H, Kido K, Uchida T, Ueda W. Preoperative stellate ganglion blockade prevents tourniquet-induced hypertension during general anesthesia. Acta Anaesthesiol Scand. 2004 May;48(5):613-8. doi: 10.1111/j.0001-5172.2004.00389.x.

Reference Type BACKGROUND
PMID: 15101858 (View on PubMed)

Other Identifiers

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XYFY2017-KL012-01

Identifier Type: -

Identifier Source: org_study_id

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