Dexmedetomidine Premedication in Children

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-03-01

Study Completion Date

2017-05-25

Brief Summary

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The aim of this retrospective study was to detect the effectiveness of 1µg/kg oral dexmedetomidine premedication on preoperative cooperation and emergence delirium of the the young children underwent complete dental treatment.

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Detailed Description

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One Hundred children between the ages 2-6 years of ASA I status underwent full mouth dental rehabilitation were enrolled in the study. Group Dex (n=50) received 1µg/kg dexmedetomidine in apple juice and Group control (n=50) received apple juice only. Patients' Ramsey Sedation Scale (RSS), The Parental Seperation Anxiety Scale (PSAS), Mask Acceptance Scale (MAS) and Post anesthesia emergence delirium scale (PAEDS) and hemodynamic parameters were noted from their patient file. Premedication period was 45 minutes and measurements of RSS and hemodynamic parameters were recorded in baseline and every 15 minutes until the patients were transferred to the operating room. The data were analysed using the Kruskal-Wallis test, two sample t- tests, chi-square tests and ANOVA.

Conditions

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Premedication

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Retrospective study

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Investigators

Investigator

Study Groups

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Dexmedetomidine

Group administered 1µg/kg dexmedetomidine oral

Group Type EXPERIMENTAL

Dexmedetomidine

Intervention Type DRUG

1µg/kg dexmedetomidine oral

Control

Apple juice

Group Type OTHER

apple juice

Intervention Type OTHER

apple juice

Interventions

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Dexmedetomidine

1µg/kg dexmedetomidine oral

Intervention Type DRUG

apple juice

Intervention Type OTHER

Other Intervention Names

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Precedex

Eligibility Criteria

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Inclusion Criteria

Inclusion Criteria:

* The inclusion criteria is age between 2 to 6 years and American Society og Anesthesiology (ASA) grade 1.

Exclusion Criteria:

* The exclusion criteria included congenital disease, DEX, propofol allergy, asthma, mental retardation and those children parents refuse to participate study.

Minimum Eligible Age

2 Years

Maximum Eligible Age

6 Years

Eligible Sex

Accepts Healthy Volunteers

Yes