GDFT Based on PPV Compared With Standard Fluid Therapy in Patients Undergoing Complex Spine Surgery: RCT
NCT ID: NCT03164811
Last Updated: 2020-02-05
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
60 participants
INTERVENTIONAL
2017-04-11
2019-01-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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GDFT group
The GDFT group will receive 400 ml of 12.5% carbohydrate drink after 6 pm until the bed time in the day before surgery and 200 ml in the morning of the surgery day. Acetate ringer solution will be start at 7:00. After induction PPV will be measure and fluid bolus 200 ml in 10 minutes will be given if PPV \>13 before prone position. During the operation, the patient in GDFT group will receipt fluid therapy according to acceptable PPV
goal directed fluid therapy
pulse pressure variation will be used to as a goal to guide fluid administration in this group
controlled group
The carbohydrate drink will not be given. Fluid, blood and blood product administration will be under attending anesthesiologist order.
Controlled
standard fluid treatment by an anesthesiologist
Interventions
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goal directed fluid therapy
pulse pressure variation will be used to as a goal to guide fluid administration in this group
Controlled
standard fluid treatment by an anesthesiologist
Eligibility Criteria
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Inclusion Criteria
* elective surgery
* thoracic/lumbar spine surgery \>= 3 levels and duration \>= 3 hours
Exclusion Criteria
* coronary artery disease, congestive heart failure or cardiac arrhythmia
* BMI \>30 kg/m2
* hemodynamic unstable, preoperatively
* uncontrolled hypertension
* respiratory system compliance \< 30 ml/cmH2O
18 Years
70 Years
ALL
No
Sponsors
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Mahidol University
OTHER
Responsible Party
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Locations
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Faculty of Medicine Siriraj Hospital
Bangkok Noi, Bangkok, Thailand
Countries
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Other Identifiers
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Si826/2016
Identifier Type: -
Identifier Source: org_study_id
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