Preoperative Anxiety's Incidence and Related Factors in Surgical Patients
NCT ID: NCT03162692
Last Updated: 2017-05-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
2000 participants
OBSERVATIONAL
2017-04-01
2018-02-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
* Sign that informed consent is willing to participate in the study
* Education: primary school and above
* 1 days after elective general anesthesia surgery
* ASA score grade I-III
Exclusion Criteria
* Severe mental illness patients (such as anxiety, depression, schizophrenia, etc.)
* Taking anti-anxiety or antidepressants (benzodiazepines, tricyclic antidepressants, selective serotonin inhibitors, monoamine oxidase inhibitors, etc.)
18 Years
70 Years
ALL
Yes
Sponsors
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Xuzhou Medical University
OTHER
Responsible Party
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Jin Dong Liu
Chief physician and Associate Professor
Principal Investigators
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Jindong Liu, M.S
Role: PRINCIPAL_INVESTIGATOR
The Affiliated Hospital of Xuzhou Medical University
Locations
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The Affiliated Hospital of Xuzhou Medical University
Xuzhou, Jiangsu, China
Countries
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Central Contacts
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Facility Contacts
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References
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Lieb K, Fiebich BL, Berger M. [Substance P receptor antagonists--a new antidepressive and anxiolytic mechanism?]. Nervenarzt. 2000 Sep;71(9):758-61. doi: 10.1007/s001150050661. German.
Maki Y. [A behavioral and neurochemical study on the mechanism of the anxiolytic effect of monoamine oxidase inhibitors]. Hokkaido Igaku Zasshi. 2001 May;76(3):133-42. Japanese.
Yamauchi M, Hiraoka S, Imanishi T. [Role of the serotonergic nervous system in anxiety disorders and the anxiolytic mechanism of selective serotonin reuptake inhibitors]. Nihon Shinkei Seishin Yakurigaku Zasshi. 2006 Nov;26(5-6):193-8. Japanese.
Matsumoto K, Puia G, Dong E, Pinna G. GABA(A) receptor neurotransmission dysfunction in a mouse model of social isolation-induced stress: possible insights into a non-serotonergic mechanism of action of SSRIs in mood and anxiety disorders. Stress. 2007 Mar;10(1):3-12. doi: 10.1080/10253890701200997.
Herrera-Ruiz M, Gonzalez-Carranza A, Zamilpa A, Jimenez-Ferrer E, Huerta-Reyes M, Navarro-Garcia VM. The standardized extract of Loeselia mexicana possesses anxiolytic activity through the gamma-amino butyric acid mechanism. J Ethnopharmacol. 2011 Nov 18;138(2):261-7. doi: 10.1016/j.jep.2011.09.010. Epub 2011 Sep 16.
Mico JA, Prieto R. Elucidating the mechanism of action of pregabalin: alpha(2)delta as a therapeutic target in anxiety. CNS Drugs. 2012 Aug 1;26(8):637-48. doi: 10.2165/11634510-000000000-00000.
O'Donovan A, Slavich GM, Epel ES, Neylan TC. Exaggerated neurobiological sensitivity to threat as a mechanism linking anxiety with increased risk for diseases of aging. Neurosci Biobehav Rev. 2013 Jan;37(1):96-108. doi: 10.1016/j.neubiorev.2012.10.013. Epub 2012 Nov 2.
Fan JM, Chen XQ, Du JZ. Prenatal stress, anxiety and depression: a mechanism involving CRH peptide family. Neuro Endocrinol Lett. 2014;35(6):429-39.
He W, Zhou Q, Yu S, Cai D, Wang Q, Zhang X, Huang WQ. [Mechanism on atrial natriuretic peptide receptor in anti-anxiety with acupuncture based on its tranquilizing effect]. Zhongguo Zhen Jiu. 2015 Jan;35(1):101-4. Chinese.
Other Identifiers
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XYFY2017-KL021-01
Identifier Type: -
Identifier Source: org_study_id
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